Cas no 28485-17-8 (ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate)
ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- Ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate
- 5-Carbethoxyuracil
- Ethyl uracil-5-carboxylate
- 5-CARBETHOXYURACI
- 5-Pyrimidinecarboxylic acid, 1,2,3,4- tetrahydro-2,4-dioxo-, ethyl ester
- Ethyl 2,4-dihydroxypyrimidine-5-carboxylate
- ethyl 2,4-dioxo-1H-pyrimidine-5-carboxylate
- 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester
- 5-ethoxycarbonyluracil
- ethyl 1,2,3,4-tetrahydro-2,4-dioxopyrimidine-5-carboxylate
- ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
- ethyl tetrahydropyrimidine-2,4(1H,3H)-dione-5-carboxylate
- Isoorotic acid ethyl ester
- 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, ethyl ester
- Ethyl 4-hydroxy-2-oxo-1,2-dihydropy
- BCP32285
- BP-12770
- W-202192
- MFCD00057337
- EINECS 249-053-3
- AKOS015919488
- AKOS006280946
- 5-Carbethoxyuracil, ~90%
- NSC 513173
- NS00028495
- SB57318
- FT-0620189
- MKNYHTGOVKPZMU-UHFFFAOYSA-N
- Uracil-5-carboxylic acid ethyl ester
- SY003624
- GS-6539
- AMY5247
- J-640435
- AC-3033
- NSC513173
- Methyl uracil-5-carboxylate;Isoorotic acid ethyl ester;Ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate
- A18572
- AM87654
- CS-0042918
- 28485-17-8
- J-800173
- 5-ethoxycarbonyl-pyrimidine-2,6-dione
- AKOS003107094
- Ethyl 4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate
- SCHEMBL124965
- NSC-513173
- DTXSID40182713
- ALBB-030439
- ETHYL 2,4-DIOXO-1,3-DIHYDROPYRIMIDINE-5-CARBOXYLATE
- DB-008895
-
- MDL： MFCD00047363
- Inchi： 1S/C7H8N2O4/c1-2-13-6(11)4-3-8-7(12)9-5(4)10/h3H,2H2,1H3,(H2,8,9,10,12)
- InChI Key： MKNYHTGOVKPZMU-UHFFFAOYSA-N
- SMILES： O(CC)C(C1=CNC(NC1=O)=O)=O
Computed Properties
- Exact Mass: 184.04800
- Monoisotopic Mass: 184.048407
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 13
- Rotatable Bond Count: 3
- Complexity: 295
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 12
- XLogP3: -0.5
- Topological Polar Surface Area: 84.5
Experimental Properties
- Color/Form: White crystal powder
- Density: 1.344
- Melting Point: 232-235 oC
- Boiling Point: 398℃ at 760 mmHg
- Flash Point: 194.5℃
- Refractive Index: 1.504
- PSA: 92.02000
- LogP: -0.76010
- Solubility: Not determined
ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Safety Instruction： S22-S24/25
- Safety Term：S22;S24/25
- Storage Condition：Ambient temperatures.
ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Customs Data
- HS CODE：2933599090
- Customs Data：
China Customs Code:
2933599090Overview:
2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C300683-1g |
ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
28485-17-8 | 98% | 1g |
￥86.90 | 2023-09-03 | |
| Fluorochem | 092561-250mg |
Ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate |
28485-17-8 | 95% | 250mg |
￡17.00 | 2022-02-28 | |
| Fluorochem | 092561-1g |
Ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate |
28485-17-8 | 95% | 1g |
￡28.00 | 2022-02-28 | |
| Fluorochem | 092561-10g |
Ethyl4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate |
28485-17-8 | 95% | 10g |
￡68.00 | 2022-02-28 | |
| TRC | C178023-100mg |
5-Carbethoxyuracil |
28485-17-8 | 100mg |
$ 64.00 | 2023-04-18 | ||
| TRC | C178023-250mg |
5-Carbethoxyuracil |
28485-17-8 | 250mg |
$ 75.00 | 2023-04-18 | ||
| TRC | C178023-500mg |
5-Carbethoxyuracil |
28485-17-8 | 500mg |
$ 87.00 | 2023-04-18 | ||
| TRC | C178023-1g |
5-Carbethoxyuracil |
28485-17-8 | 1g |
$ 98.00 | 2023-04-18 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | C835890-5g |
5-Carbethoxyuracil |
28485-17-8 | 98% | 5g |
1,652.40 | 2021-05-17 | |
| Matrix Scientific | 150491-1g |
Ethyl 2,4-dihydroxypyrimidine-5-carboxylate, 95% |
28485-17-8 | 95% | 1g |
$86.00 | 2023-09-06 |
ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Suppliers
Audited Supplier
Audited Supplier
ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Related Literature
-
Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
-
Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
-
Eunice Y.-L. Hui,Bhimsen Rout,Yaw Sing Tan,Kok-Ping Chan,Charles W. Johannes Org. Biomol. Chem., 2018,16, 389-392
-
L. Di Michele,D. Fiocco,F. Varrato,E. Eiser,G. Foffi Soft Matter, 2014,10, 3633-3648
Additional information on ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Comprehensive Overview of Ethyl 2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate (CAS No. 28485-17-8)
Ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS No. 28485-17-8) is a versatile heterocyclic compound widely used in pharmaceutical and organic synthesis. Its molecular structure features a pyrimidine core with ester and keto functionalities, making it a valuable intermediate for drug development, particularly in the synthesis of nucleoside analogs and antiviral agents. Researchers and industries prioritize this compound due to its reactivity and compatibility with diverse chemical transformations.
In recent years, the demand for ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate has surged, driven by its applications in medicinal chemistry and bioconjugation. A trending topic in scientific forums revolves around its role in designing COVID-19 therapeutic candidates, as pyrimidine derivatives are explored for their potential to inhibit viral replication. This aligns with frequent search queries like "pyrimidine-based antiviral drugs" or "CAS 28485-17-8 applications", reflecting user interest in pandemic-related research.
The compound’s synthetic utility extends to peptide modification and fluorescence labeling, areas gaining traction in proteomics and diagnostics. SEO-optimized terms such as "heterocyclic building blocks for drug discovery" or "ethyl pyrimidine carboxylate uses" highlight its relevance. Analytical techniques like HPLC and NMR are commonly employed to verify its purity, a detail frequently searched by quality control professionals.
From an environmental perspective, ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate is noted for its biodegradability under controlled conditions, addressing the growing demand for green chemistry solutions. This aspect resonates with queries like "sustainable pharmaceutical intermediates", catering to eco-conscious researchers. Regulatory compliance data, such as REACH registration status, further enhances its marketability.
Innovative applications include its use in metal-organic frameworks (MOFs) for catalytic processes, a hotspot in materials science. The compound’s electron-deficient pyrimidine ring facilitates interactions with metal ions, a feature explored in journals and patents. Such advancements align with search trends like "CAS 28485-17-8 in MOF synthesis", demonstrating its interdisciplinary appeal.
In summary, ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS No. 28485-17-8) bridges gaps between academia and industry, offering solutions for drug design, diagnostics, and sustainable chemistry. Its multifaceted roles ensure continued relevance in evolving scientific landscapes.
28485-17-8 (ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate) Related Products
- 94820-42-5(5-Pyrimidinecarboxylicacid, 1-butyl-1,2,3,6-tetrahydro-2,6-dioxo-, ethyl ester)
- 59299-01-3(Uracil 5-carboxylic acid)
- 33458-27-4(Ethyl 2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate)
- 88468-97-7(Methyl 1,3-dimethyl-2,4-dioxopyrimidine-5-carboxylate)
- 23945-44-0(2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid)
- 98277-03-3(2,4(1H,3H)-Pyrimidinedione,5-[(acetyloxy)methyl]-)
- 69727-34-0(Uracil-5-carboxylic acid monohydrate)
- 13345-19-2(5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, ion(1-) (9CI))
- 76821-79-9(2,4-Dihydroxypyrimidine-5-carboxylic acid)
- 42821-92-1(Methyl 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate)
