Production Method 1

2613-30-1

57946-56-2

2613-33-4

878285-12-2

367-22-6

69411-06-9

Reaction Conditions

1.1 Reagents: Trifluoromethanesulfonic acid ,  Fluorine ;  rt
1.2 Reagents: Sodium hydroxide Solvents: Water ;  neutralized, rt

Reference

Electrophilic aromatic fluorination with fluorine: meta-Directed fluorination of anilines

Alric, J. P.; Marquet, B.; Billard, T.; Langlois, B. R., Journal of Fluorine Chemistry, 2005, 126(4), 661-667

4-chloro-2,5-difluoroaniline Preparation Products

• 4-Chloro-2-fluoroaniline (57946-56-2)
• 4-Chloro-3,5-difluoroaniline (2613-33-4)
• 4-Chloro-2,3-difluoroaniline (878285-12-2)
• 4-chloro-3-fluoro-aniline (367-22-6)
• 4-Chloro-2,6-difluoroaniline (69411-06-9)
• 4-chloro-2,5-difluoroaniline (2613-30-1)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Aniline and substituted anilines

• 2106-04-9(3-Chloro-2-fluoroaniline)
• 57946-56-2(4-Chloro-2-fluoroaniline)
• 348-65-2(5-Chloro-2,4-difluoroaniline)
• 650578-82-8(Benzenamine, 3-chloro-2-fluoro-, hydrochloride)
• 878285-12-2(4-Chloro-2,3-difluoroaniline)
• 54416-81-8(Benzenamine, 4-chloro-2-fluoro-, hydrochloride)
• 367-22-6(4-chloro-3-fluoro-aniline)
• 886762-39-6(3,4-Dichloro-2-fluoroaniline)
• 69411-06-9(4-Chloro-2,6-difluoroaniline)
• 2613-34-5(3-Chloro-2,4-difluoroaniline)