Cas no 21175-51-9 (2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate)

2-(5-Bromothiophen-2-yl)-2-oxoacetaldehyde hydrate is a brominated thiophene derivative featuring a reactive α-ketoaldehyde functionality. This compound is particularly valuable in synthetic organic chemistry as a versatile intermediate for constructing heterocyclic frameworks, pharmaceuticals, and functional materials. The presence of both an aldehyde and a ketone group enables diverse reactivity, including nucleophilic additions and condensation reactions, while the bromine substituent facilitates further functionalization via cross-coupling methodologies. The hydrate form enhances stability and handling, making it suitable for controlled synthetic applications. Its structural features make it a useful precursor in the development of bioactive molecules and advanced materials, particularly in medicinal and materials chemistry research.
2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate structure
21175-51-9 structure
Product Name:2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate
CAS No:21175-51-9
MF:C6H5BrO3S
MW:237.071099996567
CID:911255
PubChem ID:44118546
Update Time:2025-10-19

2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate Chemical and Physical Properties

Names and Identifiers

    • 2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate
    • 2-(5-bromothiophen-2-yl)-2-oxoacetaldehydehydrate
    • AKOS015935072
    • DS-3509
    • (5-Bromothiophen-2-yl)(oxo)acetaldehyde--water (1/1)
    • 1170045-14-3
    • 2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde;hydrate
    • DTXSID30656872
    • J-013902
    • (5-Bromothien-2-yl)glyoxal hydrate
    • 21175-51-9
    • AB48670
    • Inchi： 1S/C6H3BrO2S.H2O/c7-6-2-1-5(10-6)4(9)3-8;/h1-3H;1H2
    • InChI Key： FEJAPSSZHPASMZ-UHFFFAOYSA-N
    • SMILES： BrC1=CC=C(C(C=O)=O)S1.O

Computed Properties

  • Exact Mass: 235.91428g/mol
  • Monoisotopic Mass: 235.91428g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 160
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 63.4?2

2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHENG KE LU SI SHENG WU JI SHU
sc-357036-1 g
5-Bromo-2-thiopheneglyoxal hydrate,
 21175-51-9
1g
 ￥1,918.00 2023-07-10
SHENG KE LU SI SHENG WU JI SHU
sc-357036-1g
5-Bromo-2-thiopheneglyoxal hydrate,
 21175-51-9
1g
 ￥1918.00 2023-09-05

2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Selenium dioxide ,  Water Solvents: 1,4-Dioxane ;  5 h, 80 °C
Reference
Substrate-Controlled Three-Component Synthesis of Diverse Fused Heterocycles
Peshkov, Anatoly A.; Gapanenok, Diana; Puzyk, Aleksandra; Amire, Niyaz; Novikov, Alexander S. ; et al, Journal of Organic Chemistry, 2023, 88(15), 10508-10524

2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate Raw materials

2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate Preparation Products

2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate Related Literature

21175-51-9 (2-(5-bromothiophen-2-yl)-2-oxoacetaldehyde hydrate) Related Products

Recommended suppliers
Essenoi Fine Chemical Co., Limited
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd
Shenzhen Yaoyuan R&D Center Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shenzhen Yaoyuan R&D Center Co.,Ltd
Shanghai Aoguang Biotechnology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shanghai Aoguang Biotechnology Co., Ltd
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.