Cas no 204316-32-5 (Fmoc-Dab(Alloc)-OH)
Fmoc-Dab(Alloc)-OH is a protected amino acid derivative widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The compound features an Fmoc (9-fluorenylmethoxycarbonyl) group for α-amine protection and an Alloc (allyloxycarbonyl) group for side-chain protection of the diamino butyric acid (Dab) residue. This dual protection allows for selective deprotection under mild conditions, enabling orthogonal synthesis strategies. The Alloc group can be removed via palladium-catalyzed deprotection without affecting the Fmoc group, facilitating sequential peptide elongation. Its high purity and stability make it a reliable building block for constructing complex peptides, particularly those requiring selective side-chain modifications or branched architectures.
Fmoc-Dab(Alloc)-OH structure
Product Name:Fmoc-Dab(Alloc)-OH
CAS No:204316-32-5
MF:C23H24N2O6
MW:424.446466445923
MDL:MFCD00798634
CID:66688
PubChem ID:24888982
Update Time:2025-06-09
Fmoc-Dab(Alloc)-OH Chemical and Physical Properties
Names and Identifiers
-
- Fmoc-Dab(Alloc)
- Fmoc-Dab(Aloc)-OH
- Fmoc-4-allyloxycarbonyl-L-2,4- diaminobutyric acid
- Fmoc-Dab(Alloc)-OH
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(((allyloxy)carbonyl)amino)butanoic acid
- Fmoc-(N-gamma-allyloxycarbonyl)-L-alpha,gamma-diaminobutyric acid
- FMoc-Dab(Alloc)-OHN-α-FMoc-N-γ-allyloxycarbonyl-L-2,4-diaMinobutyric acid
- Fmoc-Daba(Aloc)-OH
- Fmoc-L-Dab(Aloc)-OH
- N-α-Fmoc-N-γ-allyloxycarbonyl-L-2,4-diaminobutyric acid
- AmbotzFAA1363
- FMOC-(N-Γ-ALLYLOXYCARBONYL)-L-Α
- Nalpha-Fmoc-Ngamma-Alloc-L-2,4-diaminobutyric acid
- Ngamma-Alloc-Nalpha-Fmoc-L-2,4-diaminobutyric acid
- Γ-DIAMINOBUTYRIC ACID
- Fmoc-L-Dab(Alloc)-OH
- 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino-3-[[(2-propenyloxy)carbonyl]amino]-L-butyric acid
- N-alpha-Fmoc-N-gamma-Alloc-L-diaminobutyric acid
- N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-gamma-allyloxycarbonyl-L-2,4-diaminobutyric acid
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(prop-2-enoxycarbonylamino)butanoic acid
- 0480AB
- AMY22629
- DS-15065
- N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-gamma-allyloxycarbonyl-L-2,4-diaminobutyric acid (Fmoc-L-Dab(Alloc)-OH)
- (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{[(prop-2-en-1-yloxy)carbonyl]amino}butanoic acid
- Butanoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-[[(2-propen-1-yloxy)carbonyl]amino]-, (2S)-
- Na-Fmoc-N?-Alloc-L-2,4-diaminobutyric acid
- DTXSID10373237
- Fmoc-Dab(Alloc)-OH, >=99.0%
- AKOS015893071
- 204316-32-5
- A850888
- SCHEMBL178810
- (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(allyloxycarbonylamino)butanoic acid
- (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-({[(prop-2-en-1-yl)oxy]carbonyl}amino)butanoic acid
- A-Fmoc-N-
- s10912
- MFCD00798634
- EN300-7374627
- A-allyloxycarbonyl-L-2,4-diaminobutyric acid
- N-
- CS-W013855
- (2S)-4-{[(Allyloxy)carbonyl]aMino}-2-{[(9H-fluoren-9-ylMethoxy)carbonyl]aMino}butanoic acid
- J-013310
- (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-{[(prop-2-en-1-yloxy)carbonyl]amino}butanoic acid
-
- MDL： MFCD00798634
- Inchi： 1S/C23H24N2O6/c1-2-13-30-22(28)24-12-11-20(21(26)27)25-23(29)31-14-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h2-10,19-20H,1,11-14H2,(H,24,28)(H,25,29)(H,26,27)/t20-/m0/s1
- InChI Key： YIVBOSPUFNDYMF-FQEVSTJZSA-N
- SMILES： O(C(N[C@H](C(=O)O)CCNC(=O)OCC=C)=O)CC1C2C=CC=CC=2C2C=CC=CC1=2
Computed Properties
- Exact Mass: 424.16300
- Monoisotopic Mass: 424.163
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 31
- Rotatable Bond Count: 11
- Complexity: 632
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 4
- XLogP3: 3.4
- Topological Polar Surface Area: 114
Experimental Properties
- Color/Form: No data available
- Density: 1.275
- Melting Point: No data available
- Boiling Point: 676.7±55.0 °C at 760 mmHg
- Flash Point: 363.1±31.5 °C
- Refractive Index: 1.589
- PSA: 113.96000
- LogP: 4.06240
Fmoc-Dab(Alloc)-OH Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - WGK Germany：3
- Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- FLUKA BRAND F CODES：10
- HazardClass：IRRITANT
- Storage Condition：Store at 4°C,-4At ℃Store…Better
Fmoc-Dab(Alloc)-OH Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM251148-5g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 5g |
$204 | 2021-06-09 | |
| Chemenu | CM251148-10g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 10g |
$337 | 2021-06-09 | |
| Chemenu | CM251148-25g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 25g |
$673 | 2021-06-09 | |
| Chemenu | CM251148-100g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 100g |
$1683 | 2021-06-09 | |
| Apollo Scientific | OR962282-1g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 1g |
￡53.00 | 2025-02-20 | |
| Apollo Scientific | OR962282-5g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 5g |
￡132.00 | 2025-02-20 | |
| Apollo Scientific | OR962282-25g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 25g |
￡542.00 | 2025-02-20 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R022350-1g |
Fmoc-Dab(Alloc)-OH,99% |
204316-32-5 | 99% | 1g |
￥222 | 2024-05-25 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R022350-5g |
Fmoc-Dab(Alloc)-OH,99% |
204316-32-5 | 99% | 5g |
￥937 | 2024-05-25 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | F20050-1g |
Fmoc-Dab(Alloc)-OH |
204316-32-5 | 98% | 1g |
￥132.0 | 2023-09-07 |
Fmoc-Dab(Alloc)-OH Related Literature
-
Eranthie Weerapana,Barbara Imperiali Org. Biomol. Chem. 2003 1 93
-
Nicholas Barlow,Sudarsana Reddy Vanga,Jonas S?vmarker,Anja Sandstr?m,Peta Burns,Anders Hallberg,Johan ?qvist,Hugo Gutiérrez-de-Terán,Mathias Hallberg,Mats Larhed,Siew Yeen Chai,Philip E. Thompson RSC Med. Chem. 2020 11 234
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Vincent E. Zwicker,Benjamin M. Long,Katrina A. Jolliffe Org. Biomol. Chem. 2015 13 7822
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