Production Method 1

5720-06-9

956100-63-3

2033056-58-3

Reaction Conditions

1.1 Reagents: Sodium carbonate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ,  Water ;  16 h, 80 °C

Reference

Fused ring pyrimidine compound, intermediate, and preparation method, composition and use thereof

, World Intellectual Property Organization, , ,

Production Method 2

190788-60-4

956100-63-3

2033056-58-3

Reaction Conditions

1.1 Reagents: Sodium carbonate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ,  Water ;  16 h, 80 °C

Reference

Condensed-ring pyrimidylamino derivatives, preparation method therefor, and intermediate, pharmaceutical composition and applications in the treatment of cancer

, World Intellectual Property Organization, , ,

2-Chloro-8-(2-methoxyphenyl)quinazoline Raw materials

• 2-Methoxyphenylboronic Acid Pinacol Ester
• 2-Methoxyphenylboronic acid
• 8-Bromo-2-chloroquinazoline

2-Chloro-8-(2-methoxyphenyl)quinazoline Preparation Products

• 2-Chloro-8-(2-methoxyphenyl)quinazoline (2033056-58-3)

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