Cas no 193353-34-3 (2,5-Difluorophenylboronic acid)
2,5-Difluorophenylboronic acid is a boronic acid derivative featuring two fluorine substituents at the 2- and 5-positions of the phenyl ring. This compound is widely utilized as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of biaryl structures with high selectivity and efficiency. The electron-withdrawing fluorine atoms enhance the reactivity of the boronic acid group while also influencing the electronic properties of the resulting products. Its stability under typical coupling conditions and compatibility with various functional groups make it a valuable reagent in pharmaceutical and materials chemistry. The compound is typically supplied as a white to off-white crystalline solid, ensuring consistent performance in synthetic applications.
193353-34-3 structure
Product Name:2,5-Difluorophenylboronic acid
CAS No:193353-34-3
MF:C6H5BF2O2
MW:157.910508871078
MDL:MFCD01863171
CID:66448
PubChem ID:2734335
Update Time:2025-06-09
2,5-Difluorophenylboronic acid Chemical and Physical Properties
Names and Identifiers
-
- 2,5-Difluorophenylboronic acid
- 2,5-Difluorophenylboronic Acid (contains varying amounts of Anhydride)
- 2,5-Difluorobenzeneboronic acid
- (2,5-Difluorophenyl)boronic acid
- Cyclopropyl 2-fluorobenzyl ketone
- (2,5-difluorophenyl)boranediol
- 2,4-DIFLUOROPHENETHYLAMINE
- 2,5-Difluorob
- 2,5-fluorobenzene boronic acid
- 2,5-Difluorobenzeneboronic Acid (contains varying amounts of Anhydride)
- AKOS BRN-0301
- RARECHEM AH PB 0165
- 2,5-DIFLUOROPHENYLBO
- 5-Difluorophenylboronic acid
- 2,5-Diflurorbenzene boronic acid
- 2,5-Difluorobenzeneboronicacid98%
- 2,5-Difluorophenylboronic acid,97%
- 2,5-Difluorophenylboronicacid
- BORONIC ACID, (2,5-DIFLUOROPHENYL)-
- PubChem1820
- KSC174I6R
- 2,5-difluoro phenylboronic acid
- 2,5-difluorophenyl-boronic acid
- 2,5-difluorophenyl boronic acid
- 2,5-difluoro-phenylboronic acid
- 2,5-difluorobenzene boronic acid
- KT
- 25-Difluorophenylboronic acid
- J-507344
- AC-5378
- FT-0610350
- SY005772
- KTOJGSDLJNUAEP-UHFFFAOYSA-N
- CS-0007591
- EN300-117464
- Z381541020
- A16025
- DS-0468
- (2,5-difluorophenyl)boronicAcid
- DTXSID10370226
- SCHEMBL4963
- AKOS000285052
- 193353-34-3
- MFCD01863171
- AM20060168
- HY-32884
- D3436
- STL557890
- DB-027640
- BBL104075
-
- MDL： MFCD01863171
- Inchi： 1S/C6H5BF2O2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,10-11H
- InChI Key： KTOJGSDLJNUAEP-UHFFFAOYSA-N
- SMILES： FC1C=CC(=CC=1B(O)O)F
- BRN： 8833254
Computed Properties
- Exact Mass: 158.03500
- Monoisotopic Mass: 158.035
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 134
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 40.5
Experimental Properties
- Color/Form: solid
- Density: 1.3500
- Melting Point: 105-110?°C (lit.)
- Boiling Point: 271.3℃ at 760 mmHg
- Flash Point: 117.9℃
- Refractive Index: 1.533
- PSA: 40.46000
- LogP: -0.35540
- Solubility: Not determined
2,5-Difluorophenylboronic acid Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315-H319
- Warning Statement： P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： R22;R36/37/38
- Safety Instruction： S37/39-S26
-
Hazardous Material Identification：
- Safety Term：S26;S37/39
- Risk Phrases：R22; R36/37/38
- HazardClass：IRRITANT
- Storage Condition：Store at room temperature
2,5-Difluorophenylboronic acid Customs Data
- HS CODE：2931900090
- Customs Data：
China Customs Code:
2931900090Overview:
2931900090. Other organic-Inorganic compound. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:6.5%. general tariff:30.0%
Summary:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
2,5-Difluorophenylboronic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D3436-5g |
2,5-Difluorophenylboronic acid |
193353-34-3 | contains varying amounts of Anhydride) | 5g |
￥250.0 | 2022-09-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D3436-25g |
2,5-Difluorophenylboronic acid |
193353-34-3 | contains varying amounts of Anhydride) | 25g |
￥990.0 | 2022-09-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D680A-25g |
2,5-Difluorophenylboronic acid |
193353-34-3 | 98% | 25g |
￥340.0 | 2022-09-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D680A-1g |
2,5-Difluorophenylboronic acid |
193353-34-3 | 98% | 1g |
￥45.0 | 2022-09-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | D680A-5g |
2,5-Difluorophenylboronic acid |
193353-34-3 | 98% | 5g |
￥86.0 | 2022-09-28 | |
| Fluorochem | 033091-5g |
2,5-Difluorophenylboronic acid |
193353-34-3 | 97% | 5g |
￡13.00 | 2022-02-28 | |
| Fluorochem | 033091-10g |
2,5-Difluorophenylboronic acid |
193353-34-3 | 97% | 10g |
￡22.00 | 2022-02-28 | |
| Fluorochem | 033091-25g |
2,5-Difluorophenylboronic acid |
193353-34-3 | 97% | 25g |
￡39.00 | 2022-02-28 | |
| Fluorochem | 033091-100g |
2,5-Difluorophenylboronic acid |
193353-34-3 | 97% | 100g |
￡150.00 | 2022-02-28 | |
| Alichem | A242000627-250mg |
2,5-Difluorophenylboronic acid |
193353-34-3 | 98% | 250mg |
$727.60 | 2023-09-02 |
2,5-Difluorophenylboronic acid Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:193353-34-3)2,5-DIFLUOROPHENYLBORONIC ACID
Order Number:sfd15935
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:37
Price ($):discuss personally
Email:[email protected]
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:193353-34-3)2,5-Difluorophenylboronic acid
Order Number:A16025
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:04
Price ($):517.0
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:193353-34-3)2,5-二氟苯硼酸
Order Number:LE2466924
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:38
Price ($):discuss personally
Email:[email protected]
2,5-Difluorophenylboronic acid Related Literature
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1. Elongated phosphoranes by C–C coupling of haloaroylmethylidenetriphenylphosphoranes: synthesis and applicationsThies Thiemann,Kuniharu Umeno,Jian Wang,Yumiko Tabuchi,Kazuya Arima,Masataka Watanabe,Yasuko Tanaka,Hideki Gorohmaru,Shuntaro Mataka J. Chem. Soc. Perkin Trans. 1 2002 2090
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Takuya Konno,Hiroki Kudo,Takayuki Ishida J. Mater. Chem. C 2015 3 7813
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Lauren M. Stencel,Chad M. Kormos,Keri B. Avery,Nicholas E. Leadbeater Org. Biomol. Chem. 2009 7 2452
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