Cas no 189882-33-5 (1H-pyrrolo[2,3-b]pyridine-6-carbonitrile)
1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile is a heterocyclic organic compound featuring a fused pyrrolopyridine core with a nitrile functional group at the 6-position. This structure serves as a versatile intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of kinase inhibitors and other biologically active molecules. Its rigid bicyclic framework enhances binding affinity in target interactions, while the nitrile group offers reactivity for further derivatization. The compound exhibits favorable stability and solubility properties, facilitating its use in medicinal chemistry research. Its synthetic utility lies in its ability to act as a precursor for a range of functionalized heterocycles, making it valuable for drug discovery applications.
![1H-pyrrolo[2,3-b]pyridine-6-carbonitrile structure](https://ossimg.kuujia.com/scimg/190000/189882-33-5x500.png)
189882-33-5 structure
Product Name:1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
CAS No:189882-33-5
MF:C8H5N3
MW:143.145400762558
MDL:MFCD06659673
CID:827424
PubChem ID:10534776
Update Time:2025-10-28
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Chemical and Physical Properties
Names and Identifiers
-
- 6-Cyano-7-azaindole
- 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile
- 6-Cyano-1H-pyrrolo[2,3-b]pyridine
- PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE
- 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile(9CI)
- 6-CYANO-7-AZA-INDOLE
- PubChem19914
- GAFBPZMOMITHLG-UHFFFAOYSA-N
- BCP21349
- RP09258
- CM14080
- PB30842
- LS20802
- BC665960
- AB0023091
- ST2418943
- 6-CYANO-1H-PYRROLO[2,3B]PYRIDINE
- W4085
- KS-
- 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
-
- MDL： MFCD06659673
- Inchi： 1S/C8H5N3/c9-5-7-2-1-6-3-4-10-8(6)11-7/h1-4H,(H,10,11)
- InChI Key： GAFBPZMOMITHLG-UHFFFAOYSA-N
- SMILES： N1C=CC2=CC=C(C#N)N=C12
Computed Properties
- Exact Mass: 143.04800
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 11
- Rotatable Bond Count: 0
- Complexity: 193
- Topological Polar Surface Area: 52.5
Experimental Properties
- Color/Form: White to Yellow Solid
- Boiling Point: 373.2℃ at 760 mmHg
- PSA: 52.47000
- LogP: 1.43458
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Security Information
- Signal Word：Danger
- Hazard Statement： H301;H311;H331
- Warning Statement： P261;P280;P301+P310;P311
- Storage Condition：Room temperature
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 208909-250mg |
6-Cyano-7-azaindole |
189882-33-5 | 95% | 250mg |
￡92.00 | 2022-03-01 | |
| Fluorochem | 208909-1g |
6-Cyano-7-azaindole |
189882-33-5 | 95% | 1g |
￡290.00 | 2022-03-01 | |
| Fluorochem | 208909-5g |
6-Cyano-7-azaindole |
189882-33-5 | 95% | 5g |
￡1015.00 | 2022-03-01 | |
| AstaTech | 50649-0.25/G |
6-CYANO-7-AZA-INDOLE |
189882-33-5 | 95% | 0.25g |
$39 | 2023-09-17 | |
| AstaTech | 50649-1/G |
6-CYANO-7-AZA-INDOLE |
189882-33-5 | 95% | 1g |
$99 | 2023-09-17 | |
| AstaTech | 50649-5/G |
6-CYANO-7-AZA-INDOLE |
189882-33-5 | 95% | 5g |
$349 | 2023-09-17 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | H175345-100mg |
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile |
189882-33-5 | 97% | 100mg |
￥321.90 | 2023-09-02 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | H175345-1g |
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile |
189882-33-5 | 97% | 1g |
￥1483.90 | 2023-09-02 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | H175345-25mg |
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile |
189882-33-5 | 97% | 25mg |
￥187.90 | 2023-09-02 | |
| Chemenu | CM107429-100mg |
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile |
189882-33-5 | 95%+ | 100mg |
$140 | 2021-08-06 |
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Related Literature
-
Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
-
José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
-
Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378
-
Doug Ogrin,Laura H. van Poppel,Simon G. Bott,Andrew R. Barron Dalton Trans., 2004, 3689-3694
-
Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
189882-33-5 (1H-pyrrolo[2,3-b]pyridine-6-carbonitrile) Related Products
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- 1005206-16-5(7H-Pyrrolo[2,3-d]pyrimidine-4-carbonitrile)
- 1199590-87-8(5H-Pyrrolo[2,3-b:4,5-b']dipyridine-2-carbonitrile)
- 1201790-60-4(9H-Pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile)
- 935466-70-9(4-chloro-1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile)
- 824-51-1(6-Methyl-1H-pyrrolo[2,3-b]pyridine)
- 932039-99-1(Dipyrido[2,3-b:3,2-i]anthyridine-2,9-dicarbonitrile, radical ion(1-))
- 1000340-62-4(6-Methyl-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile)
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