- An Efficient Synthesis of 1-(2-Methoxyphenoxy)-2,3-epoxypropane: Key Intermediate of β-AdrenoblockersMadivada, Lokeswara Rao; Anumala, Raghupathi Reddy; Gilla, Goverdhan; Kagga, Mukkanti; Bandichhor, Rakeshwar, Organic Process Research & Development, 2012, 16(10), 1660-1664
Cas no 16929-60-5 (1,3-Bis(2-methoxyphenoxy)-2-propanol)
1,3-Bis(2-methoxyphenoxy)-2-propanol is a synthetic organic compound characterized by its aromatic ether and alcohol functional groups. This chemical is notable for its role as an intermediate in the synthesis of specialty polymers, resins, and pharmaceuticals. Its structure, featuring two methoxyphenoxy groups attached to a propanol backbone, provides versatility in chemical modifications and cross-linking reactions. The compound exhibits favorable solubility in organic solvents, facilitating its use in formulation processes. Additionally, its stability under moderate conditions makes it suitable for applications requiring controlled reactivity. Researchers value this compound for its potential in developing advanced materials with tailored thermal and mechanical properties.
16929-60-5 structure
Product Name:1,3-Bis(2-methoxyphenoxy)-2-propanol
CAS No:16929-60-5
MF:C17H20O5
MW:304.337705612183
CID:156629
PubChem ID:329770019
Update Time:2025-06-07
1,3-Bis(2-methoxyphenoxy)-2-propanol Chemical and Physical Properties
Names and Identifiers
-
- 2-Propanol,1,3-bis(2-methoxyphenoxy)-
- 1,3-Bis(2-methoxyphenoxy)-2-propanol
- 1,3-bis-(2-methoxy-phenoxy)-propan-2-ol
- 1,3-Bis(2-methoxyphenoxy)propan-2-ol Guaifenesin impurity D (PhEur)
- 1,3-di-o-methoxyphenoxypropan-2-ol
- 1,3-Bis(2-methoxyphenoxy)propan-2-ol
- Guaifenesin impurity D (PhEur)
- NSC 142122
- Guaicol Impurity D
- Guaifenesin EP impurity D
- 1,3-Bis(o-methoxyphenoxy)-2-propanol
- Guaifenesin Imp. D (EP); 1,3-Bis(2-methoxyphenoxy)propan-2-ol; Guaifenesin Impurity D
- SCHEMBL2328960
- MFCD01697245
- 9W2WA37VTB
- NSC-142122
- 2-Propanol, 1,3-bis(o-methoxyphenoxy)-
- NSC142122
- 3-06-00-04224 (Beilstein Handbook Reference)
- 2-Propanol, 1,3-bis(2-methoxyphenoxy)-
- DTXSID90168688
- BS-46059
- CS-0150301
- 1,3-Bis(2-methoxyphenoxy)-2-propanol, pharmaceutical impurity standard
- 16929-60-5
- BRN 2003232
- GUAIFENESIN IMPURITY D [EP IMPURITY]
- D81597
- UNII-9W2WA37VTB
- GUAIFENESIN IMPURITY D (EP IMPURITY)
- DB-345513
- DTXCID7091179
-
- MDL： MFCD01697245
- Inchi： 1S/C17H20O5/c1-19-14-7-3-5-9-16(14)21-11-13(18)12-22-17-10-6-4-8-15(17)20-2/h3-10,13,18H,11-12H2,1-2H3
- InChI Key： SSNCGCIXFDVLFP-UHFFFAOYSA-N
- SMILES： O(C1C=CC=CC=1OC)CC(COC1C=CC=CC=1OC)O
Computed Properties
- Exact Mass: 304.13100
- Monoisotopic Mass: 304.131
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 22
- Rotatable Bond Count: 8
- Complexity: 271
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.9
- Topological Polar Surface Area: 57.2A^2
Experimental Properties
- Density: 1.167±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 73-74.2 oC (ethyl ether )
- Boiling Point: Not available
- Flash Point: Not available
- Refractive Index: 1.551
- Solubility: Very slightly soluble (0.58 g/l) (25 o C),
- PSA: 57.15000
- LogP: 2.52250
- Vapor Pressure: Not available
1,3-Bis(2-methoxyphenoxy)-2-propanol Security Information
-
Symbol:
- Signal Word：Warning
- Hazard Statement： H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： 36/37/38
- Safety Instruction： 26
- RTECS：UA7374000
-
Hazardous Material Identification：
- Storage Condition：Hygro°Cop°C, -20°C Freezer, Under inert atmosphere
1,3-Bis(2-methoxyphenoxy)-2-propanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B490030-25mg |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 25mg |
$ 115.00 | 2023-09-08 | ||
| TRC | B490030-50mg |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 50mg |
$ 161.00 | 2023-09-08 | ||
| TRC | B490030-100mg |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 100mg |
$ 282.00 | 2023-09-08 | ||
| TRC | B490030-250mg |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 250mg |
$ 526.00 | 2023-04-18 | ||
| TRC | B490030-1g |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 1g |
$ 945.00 | 2023-04-18 | ||
| TRC | B490030-5g |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 5g |
$ 3128.00 | 2023-04-18 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | B922338-100mg |
1,3-Bis(2-methoxyphenoxy)propan-2-ol |
16929-60-5 | 97% | 100mg |
￥477.00 | 2022-09-02 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-RJ370-50mg |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 97% | 50mg |
285.0CNY | 2021-07-17 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-RJ370-200mg |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 97% | 200mg |
704.0CNY | 2021-07-17 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-RJ370-1g |
1,3-Bis(2-methoxyphenoxy)-2-propanol |
16929-60-5 | 97% | 1g |
2468.0CNY | 2021-07-17 |
1,3-Bis(2-methoxyphenoxy)-2-propanol Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Sodium hydroxide Solvents: Water ; 30 - 45 min, 30 °C
1.2 10 - 12 h, 25 - 35 °C
1.3 Reagents: Sodium hydroxide Solvents: Water ; 5 - 6 h, 27 °C
1.2 10 - 12 h, 25 - 35 °C
1.3 Reagents: Sodium hydroxide Solvents: Water ; 5 - 6 h, 27 °C
Reference
1,3-Bis(2-methoxyphenoxy)-2-propanol Raw materials
1,3-Bis(2-methoxyphenoxy)-2-propanol Preparation Products
1,3-Bis(2-methoxyphenoxy)-2-propanol Related Literature
-
1. An integrated microfluidic 3D tumor system for parallel and high-throughput chemotherapy evaluation?Dan Liu,Rui Hu,Zhongchao Huang,Meilin Sun,Kai Han Analyst, 2020,145, 6447-6455
-
Suji Lee,Min Su Han Chem. Commun., 2021,57, 9450-9453
-
P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
-
Benjamin Gabriel Poulson,Kacper Szczepski,Joanna Izabela Lachowicz,Lukasz Jaremko,Abdul-Hamid Emwas,Mariusz Jaremko RSC Adv., 2020,10, 215-227
-
Tanya Ostapenko,Peter J. Collings,Samuel N. Sprunt,J. T. Gleeson Soft Matter, 2013,9, 9487-9498
16929-60-5 (1,3-Bis(2-methoxyphenoxy)-2-propanol) Related Products
- 538-43-2(3-Phenoxy-1,2-propanediol)
- 622-04-8(1,3-Diphenoxypropan-2-ol)
- 93-14-1(Guaifenesin)
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
Recommended suppliers
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Reagent
Shenzhen Yaoyuan R&D Center Co.,Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Amadis Chemical Company Limited
Gold Member
Audited Supplier
CN Supplier
Reagent
