• 1. An antioxidant self-healing hydrogel for 3D cell cultures?
  Lei Yang,Yuan Zeng,Haibo Wu,Chunwu Zhou,Lei Tao J. Mater. Chem. B, 2020,8, 1383-1388
• 2. An approach to 7-aza-1-phosphanorbornane complexes: strain promoted rearrangement of 1-iminylphosphirane complexes and cycloaddition with olefins?
  Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
• 3. An insight into the hybridization mechanism of hairpin DNA physically immobilized on chemically modified graphenes
  Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
• 4. An integrated cathode and solid electrolyte via in situ polymerization with significantly reduced interface resistance?
  Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
• 5. An integrated process of CO2 capture and in situ hydrogenation to formate using a tunable ethoxyl-functionalized amidine and Rh/bisphosphine system?
  Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylpropanes
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Professional Introduction to 2-Amino-4,6-di-tert-butylphenol (CAS No. 1643-39-6)

2-Amino-4,6-di-tert-butylphenol, a compound with the chemical identifier CAS No. 1643-39-6, is a significant molecule in the field of chemical and pharmaceutical research. This compound, characterized by its amino and tert-butyl substituents on a phenolic backbone, has garnered attention due to its versatile applications and potential in various biochemical pathways. The structural features of this molecule contribute to its unique reactivity and make it a valuable candidate for further exploration in drug development and industrial chemistry.

The synthesis and characterization of 2-amino-4,6-di-tert-butylphenol involve meticulous chemical processes that highlight its stability and reactivity. The presence of two tert-butyl groups at the 4 and 6 positions enhances the molecule's lipophilicity, making it an attractive candidate for membrane-interacting applications. This property is particularly relevant in the development of novel pharmaceutical agents that require efficient penetration through biological membranes.

Recent studies have demonstrated the compound's potential in antioxidant and anti-inflammatory applications. The phenolic structure of 2-amino-4,6-di-tert-butylphenol allows for scavenging reactive oxygen species (ROS), which are implicated in various pathological conditions. Research has shown that this compound can modulate inflammatory pathways by inhibiting key enzymes such as lipoxygenase and cyclooxygenase. These findings suggest that 2-amino-4,6-di-tert-butylphenol could be a promising lead compound for therapeutic intervention in chronic inflammatory diseases.

In addition to its biological activities, 2-amino-4,6-di-tert-butylphenol has been explored for its role in material science. Its structural rigidity and hydrophobic nature make it suitable for use as an additive in polymers and coatings, enhancing their thermal stability and UV resistance. This application is particularly relevant in industries where material durability under harsh environmental conditions is crucial.

The chemical properties of CAS No. 1643-39-6, particularly its solubility and thermal stability, have been extensively studied. Researchers have found that this compound exhibits high solubility in organic solvents, which facilitates its use in various chemical reactions and formulations. Furthermore, its thermal stability ensures that it can withstand high temperatures without degradation, making it a reliable component in industrial processes.

The pharmacokinetic profile of 2-amino-4,6-di-tert-butylphenol has also been a focus of recent investigations. Studies indicate that this compound has a moderate bioavailability when administered orally, with a reasonable half-life that allows for sustained activity within the body. This profile makes it an attractive candidate for oral formulations designed to treat chronic conditions.

The safety profile of CAS No. 1643-39-6 has been thoroughly evaluated through preclinical studies. These studies have demonstrated that the compound is well-tolerated at therapeutic doses, with minimal side effects observed. However, further research is needed to fully understand its long-term safety implications and potential interactions with other medications.

The industrial applications of 2-amino-4,6-di-tert-butylphenol extend beyond pharmaceuticals into agrochemicals and specialty chemicals. Its ability to act as a stabilizer and antioxidant makes it valuable in formulations designed to protect crops from environmental stressors. Additionally, its compatibility with various chemical reactions allows for its use in synthesizing complex molecules used in dyes and pigments.

The future directions for research on CAS No. 1643-39-6 include exploring its potential as a prodrug or scaffold molecule for drug design. The versatility of this compound's structure allows for modifications that could enhance its bioavailability or target specific biological pathways more effectively. Collaborative efforts between chemists and biologists are essential to unlock the full therapeutic potential of this molecule.

In conclusion, 2-amino-4,6-di-tert-butylphenol represents a multifaceted compound with significant applications in both pharmaceuticals and industrial chemistry. Its unique structural features contribute to its reactivity and functionality, making it a valuable asset in ongoing research efforts. As our understanding of its properties continues to evolve, so too will its potential applications across various scientific disciplines.

• 944356-91-6(Phenol, 2-amino-4-ethyl-6-methyl-)
• 29709-88-4(Phenol,2,4-diamino-6-(1-methylpropyl)-)
• 774502-66-8(Phenol,2-amino-4-methyl-6-(1-methylethyl)-)
• 16750-66-6(4-Amino-2-isopropylphenol)
• 950-58-3(4-Amino-2,6-DI-tert-butylphenol)
• 1988-15-4(Phenol, 4-amino-2,6-bis(1-methylethyl)-)
• 1199-46-8(2-Amino-4-tert-butylphenol)
• 29078-20-4(Phenol,2-amino-6-(1-methylethyl)-)
• 13366-69-3(Phenol,2-amino-3-methyl-6-(1-methylethyl)-)
• 746559-26-2(Phenol,2-amino-6-ethyl-4-methyl-)