Cas no 1988-15-4 (Phenol, 4-amino-2,6-bis(1-methylethyl)-)

Phenol, 4-amino-2,6-bis(1-methylethyl)-, also known as 4-amino-2,6-diisopropylphenol, is a substituted phenolic compound featuring an amino group and two isopropyl substituents at the 2- and 6-positions. This structure imparts steric hindrance and enhanced stability, making it useful as an intermediate in organic synthesis, particularly for pharmaceuticals and specialty chemicals. The electron-donating amino group and bulky isopropyl substituents influence its reactivity, enabling selective functionalization. Its high purity and well-defined molecular structure ensure consistent performance in applications such as catalyst ligands or antioxidant precursors. The compound is typically handled under controlled conditions due to its sensitivity to oxidation and potential reactivity with strong acids or bases.
Phenol, 4-amino-2,6-bis(1-methylethyl)- structure
1988-15-4 structure
Product Name:Phenol, 4-amino-2,6-bis(1-methylethyl)-
CAS No:1988-15-4
MF:C12H19NO
MW:193.285363435745
CID:1389150
PubChem ID:818538
Update Time:2025-05-28

Phenol, 4-amino-2,6-bis(1-methylethyl)- Chemical and Physical Properties

Names and Identifiers

    • Phenol, 4-amino-2,6-bis(1-methylethyl)-
    • 4-Amino-2,6-diisopropyl-phenol
    • Oprea1_560158
    • Oprea1_325657
    • HMS1679M02
    • 4-amino-2,6-bis(propan-2-yl)phenol
    • CHEMBL57165
    • 4-amino-2,6-di(propan-2-yl)phenol
    • AKOS000622475
    • SCHEMBL6868812
    • CS-0336582
    • F51071
    • EN300-8588882
    • OIYNNJHEBQIVIJ-UHFFFAOYSA-N
    • 4-amino-2,6-diisopropylphenol
    • 1988-15-4
    • Inchi: 1S/C12H19NO/c1-7(2)10-5-9(13)6-11(8(3)4)12(10)14/h5-8,14H,13H2,1-4H3
    • InChI Key: OIYNNJHEBQIVIJ-UHFFFAOYSA-N
    • SMILES: OC1C(=CC(=CC=1C(C)C)N)C(C)C

Computed Properties

  • Exact Mass: 193.14677
  • Monoisotopic Mass: 193.146664230g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 2
  • Complexity: 161
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 46.2?2

Experimental Properties

  • PSA: 46.25

Phenol, 4-amino-2,6-bis(1-methylethyl)- Pricemore >>

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Additional information on Phenol, 4-amino-2,6-bis(1-methylethyl)-

Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- (CAS No. 1988-15-4): A Comprehensive Overview

Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- (commonly referred to as 4-amino-2,6-diisopropylphenol) is a versatile organic compound with the CAS registry number 1988-15-4. This compound belongs to the class of aromatic amines and is widely recognized for its unique chemical properties and diverse applications in various industries. The molecule consists of a phenol ring substituted with an amino group at the para position and two isopropyl groups at the ortho positions. This specific substitution pattern imparts Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- with distinctive reactivity and stability.

The synthesis of Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- typically involves multi-step processes that include nucleophilic aromatic substitution or coupling reactions. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly production techniques. For instance, researchers have explored the use of palladium-catalyzed cross-coupling reactions to synthesize this compound with higher yields and selectivity. These developments highlight the ongoing efforts to optimize the production of Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- while minimizing environmental impact.

One of the most notable applications of Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- is in the pharmaceutical industry. The compound serves as an intermediate in the synthesis of various bioactive molecules, including anti-inflammatory agents and antioxidants. Recent studies have demonstrated its potential as a precursor for developing novel drugs targeting chronic diseases such as neurodegenerative disorders and cardiovascular conditions. Its ability to undergo multiple functional group transformations makes it a valuable building block in medicinal chemistry.

In addition to pharmaceutical applications, Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- finds utility in the field of materials science. It has been employed as a monomer in the synthesis of advanced polymers and composites with tailored mechanical and thermal properties. For example, researchers have investigated its use in creating high-performance thermoplastics for aerospace and automotive industries. The compound's ability to form stable polymer networks underscores its importance in modern materials development.

The chemical stability of Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- is another key attribute that contributes to its widespread use. Studies have shown that the molecule exhibits excellent resistance to oxidation and hydrolysis under various conditions. This stability is particularly advantageous in industrial settings where prolonged exposure to harsh environments is common.

From an environmental perspective, understanding the fate and transport of Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- in natural systems is crucial for assessing its potential ecological impact. Recent research has focused on evaluating its biodegradation pathways and toxicity profiles. Findings indicate that the compound undergoes rapid microbial degradation under aerobic conditions, reducing its persistence in aquatic ecosystems.

In conclusion, Phenol, 4-Amino-2,6-Bis(1-Methylethyl)- (CAS No. 1988-15-4) stands out as a multifaceted organic compound with significant contributions across multiple disciplines. Its unique chemical properties continue to drive innovation in pharmaceuticals, materials science, and environmental chemistry. As research progresses further into its applications and mechanisms of action, Phenol, 4-Amino-2,Bis(1-Methylethyl)- is poised to play an even more critical role in advancing scientific discovery and industrial development.

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