• 1. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?
  Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
• 2. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 3. Excited-state proton-coupled electron transfer within ion pairs?
  Gerald J. Meyer,Leif Hammarstr?m Chem. Sci., 2020,11, 3460-3473
• 4. Enabling non-flammable Li-metal batteries via electrolyte functionalization and interface engineering?
  Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
• 5. Emerging investigators
  Polym. Chem., 2015,6, 5501-5502

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzenes
• Solvents and Organic Chemicals Organic Compounds cyanides/Cyanides

2-Fluoro-6-nitrobenzonitrile: A Comprehensive Overview

2-Fluoro-6-nitrobenzonitrile, identified by the CAS number 143306-27-8, is a chemically synthesized compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound is characterized by its unique structure, which includes a fluorine atom at the 2-position and a nitro group at the 6-position of a benzonitrile framework. The combination of these substituents imparts distinct chemical properties, making it a valuable molecule for various applications.

The synthesis of 2-Fluoro-6-nitrobenzonitrile involves a series of well-established organic reactions, including nucleophilic substitution and nitration. Recent advancements in synthetic methodologies have enabled the efficient and scalable production of this compound, ensuring its availability for research and industrial purposes. The compound's stability under various conditions has been thoroughly investigated, with studies indicating its resistance to thermal degradation and moderate reactivity towards nucleophilic attack.

In terms of chemical properties, 2-Fluoro-6-nitrobenzonitrile exhibits a high melting point, which is attributed to the strong intermolecular forces arising from the electron-withdrawing groups present in its structure. The compound's solubility in common organic solvents has been optimized through modifications in the synthesis process, enhancing its utility in solution-based reactions. Additionally, the compound's UV-vis spectrum has been analyzed, revealing absorption bands that are indicative of its electronic structure.

The application of 2-Fluoro-6-nitrobenzonitrile spans across multiple disciplines. In pharmacology, it has been utilized as a precursor for the development of bioactive compounds with potential therapeutic applications. Recent studies have highlighted its role in the synthesis of novel anti-inflammatory agents, where its structural features contribute to enhanced bioavailability and efficacy. Furthermore, in materials science, this compound has been explored as a building block for advanced polymer systems, leveraging its ability to form stable covalent bonds.

Recent research has delved into the environmental impact of 2-Fluoro-6-nitrobenzonitrile, with studies assessing its biodegradability and toxicity profiles. Findings suggest that under controlled conditions, the compound undergoes gradual degradation via microbial action, minimizing its environmental footprint. However, further investigations are warranted to fully understand its long-term ecological effects.

In conclusion, 2-Fluoro-6-nitrobenzonitrile, CAS number 143306-27-8, stands as a versatile and intriguing compound with diverse applications across multiple scientific domains. Its unique chemical properties and synthetic accessibility make it an invaluable tool for researchers and industry professionals alike. As ongoing studies continue to uncover new insights into its potential uses and environmental behavior, this compound is poised to play an increasingly significant role in advancing scientific knowledge and technological innovation.

• 769-10-8(1-Fluoro-2-methyl-3-nitrobenzene)
• 386-66-3(2-Fluoro-1,3,5-trimethyl-4-nitrobenzene)
• 345-22-2(1-Fluoro-2,4-dimethyl-5-nitrobenzene)
• 8051-73-8(4-Fluoro-2-nitrobenzonitrile)
• 80517-21-1(4-Fluoro-2-nitrobenzonitrile)
• 34667-88-4(2-fluoro-4-nitro-benzonitrile)
• 50594-78-0(5-Fluoro-2-nitrobenzonitrile)
• 16583-05-4(Benzonitrile, 2,3,4,5-tetrafluoro-6-nitro-)
• 8051-30-7(4-Fluoro-2-nitrobenzonitrile)
• 165671-05-6(4,5-Difluoro-2-nitrobenzonitrile)