Cas no 1423031-91-7 (Isoquinolin-4-amine hydrochloride)

Isoquinolin-4-amine hydrochloride is a heterocyclic organic compound featuring an isoquinoline core with an amine functional group at the 4-position, presented as its hydrochloride salt for enhanced stability and solubility. This compound is widely utilized in pharmaceutical research and organic synthesis as a versatile intermediate, particularly in the development of bioactive molecules and medicinal chemistry applications. Its rigid aromatic structure and reactive amine group make it valuable for constructing complex scaffolds or modifying existing pharmacophores. The hydrochloride form ensures improved handling and storage characteristics. Researchers favor this derivative for its consistent purity and compatibility with a range of reaction conditions, facilitating efficient downstream transformations.
Isoquinolin-4-amine hydrochloride structure
1423031-91-7 structure
Product Name:Isoquinolin-4-amine hydrochloride
CAS No:1423031-91-7
MF:C9H9ClN2
MW:180.634160757065
MDL:MFCD09839777
CID:1031067
PubChem ID:71607415
Update Time:2025-09-27

Isoquinolin-4-amine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • Isoquinolin-4-amine hydrochloride
    • 4-Aminoisoquinoline hydrochloride
    • isoquinolin-4-amine hydrocloride
    • ISOQUINOLIN-4-AMINE HCL
    • DB-332084
    • 4-Isoquinolinamine, hydrochloride (1:1)
    • AS-47528
    • CS-0446074
    • Isoquinolin-4-amine--hydrogen chloride (1/1)
    • 4-Aminoisoquinoline HCl
    • F14134
    • SCHEMBL15910696
    • EN300-119281
    • AKOS016844831
    • Isoquinolin-4-aminehydrochloride
    • MFCD09839777
    • DTXSID20856364
    • 1423031-91-7
    • isoquinolin-4-amine;hydrochloride
    • Z1524694515
    • MDL: MFCD09839777
    • Inchi: 1S/C9H8N2.ClH/c10-9-6-11-5-7-3-1-2-4-8(7)9;/h1-6H,10H2;1H
    • InChI Key: FTZAXOHFFATABT-UHFFFAOYSA-N
    • SMILES: Cl.N1C=C(C2C=CC=CC=2C=1)N

Computed Properties

  • Exact Mass: 180.0454260g/mol
  • Monoisotopic Mass: 180.0454260g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 136
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 38.9?2

Isoquinolin-4-amine hydrochloride Pricemore >>

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Isoquinolin-4-amine hydrochloride Related Literature

Additional information on Isoquinolin-4-amine hydrochloride

Comprehensive Overview of Isoquinolin-4-amine hydrochloride (CAS No. 1423031-91-7): Properties, Applications, and Research Insights

Isoquinolin-4-amine hydrochloride (CAS No. 1423031-91-7) is a specialized organic compound belonging to the isoquinoline derivatives family, which has garnered significant attention in pharmaceutical and biochemical research. This compound, characterized by its hydrochloride salt form, offers enhanced stability and solubility, making it a valuable intermediate in synthetic chemistry. Researchers and industry professionals frequently search for terms like "isoquinoline derivatives applications", "CAS 1423031-91-7 synthesis", and "amine hydrochloride uses", reflecting its relevance in drug discovery and material science.

The structural uniqueness of Isoquinolin-4-amine hydrochloride lies in its fused bicyclic aromatic system, which is pivotal for designing molecules with biological activity. Recent studies highlight its potential in targeting enzyme inhibitors and receptor modulators, aligning with trending topics such as "precision medicine" and "small-molecule therapeutics". Its CAS registry number (1423031-91-7) is often queried in databases like PubChem and Reaxys, underscoring its importance in high-throughput screening and chemoinformatics.

From a synthetic perspective, Isoquinolin-4-amine hydrochloride is synthesized via multi-step organic reactions, including cyclization and amination processes. The compound's hydrochloride salt form improves its handling properties, a feature frequently discussed in forums on "pharmaceutical salt selection". This adaptability makes it a candidate for optimizing drug formulations, particularly in enhancing bioavailability—a hot topic in "drug delivery systems" searches.

In the context of green chemistry, researchers are exploring eco-friendly synthesis routes for isoquinoline derivatives, including CAS 1423031-91-7, to reduce environmental impact. Queries like "sustainable heterocyclic compound synthesis" and "catalysis in amine functionalization" reflect this shift. The compound’s role in metal-organic frameworks (MOFs) and catalysis further expands its utility beyond traditional pharmaceuticals.

Analytical characterization of Isoquinolin-4-amine hydrochloride involves techniques such as NMR spectroscopy, HPLC, and mass spectrometry, ensuring purity and consistency for research applications. The demand for "high-purity amine derivatives" and "analytical method validation" in peer-reviewed literature highlights the compound's stringent quality requirements. Additionally, its stability under varying pH conditions is a key focus in "excipient compatibility studies".

Emerging applications of CAS 1423031-91-7 include its use in fluorescent probes and bioimaging agents, addressing the growing interest in "molecular imaging technologies". Its aromatic system’s electron-rich nature enables interactions with biomolecules, a property leveraged in "diagnostic tool development". Such innovations align with the rise of theranostics—a fusion of therapy and diagnostics—in modern medicine.

In summary, Isoquinolin-4-amine hydrochloride (CAS No. 1423031-91-7) is a versatile compound with broad applications in drug development, materials science, and diagnostics. Its relevance to cutting-edge research topics like "targeted drug design" and "sustainable synthesis" ensures continued interest across scientific disciplines. By integrating SEO-friendly keywords such as "isoquinoline amine properties" and "CAS 1423031-91-7 applications", this overview caters to both academic and industrial audiences seeking in-depth knowledge.

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