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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Aminoquinolines and derivatives

Introduction to Isoquinolin-8-Amine (CAS No. 23687-27-6)

Isoquinolin-8-amine, also known by its CAS number 23687-27-6, is a heterocyclic aromatic compound with significant applications in various fields of chemistry and materials science. This compound belongs to the isoquinoline family, which is a bicyclic structure consisting of a benzene ring fused to a pyridine ring. The presence of an amino group (-NH?) at the 8th position of the isoquinoline framework introduces unique electronic and structural properties that make it highly versatile for both academic research and industrial applications.

The chemical structure of isoquinolin-8-amine can be represented as C??H?N?, with a molecular weight of approximately 144.19 g/mol. Its physical properties include a melting point of around 150°C and a boiling point of about 300°C under standard conditions. These characteristics make it suitable for use in high-temperature applications, such as in the synthesis of advanced materials and as an intermediate in pharmaceutical chemistry.

Recent advancements in synthetic methodologies have enabled the efficient production of isoquinolin-8-amine through various routes, including nucleophilic aromatic substitution and coupling reactions. These methods have been optimized to enhance yield and purity, making the compound more accessible for large-scale production. For instance, researchers have employed palladium-catalyzed cross-coupling reactions to synthesize isoquinolin-8-amine derivatives with tailored functionalities, opening new avenues for its application in drug discovery and material science.

In the field of materials science, isoquinolin-8-amine has been extensively studied as a precursor for the synthesis of conductive polymers and organic semiconductors. Its ability to form stable charge transfer complexes with other organic molecules has been leveraged in the development of advanced electronic devices, such as organic light-emitting diodes (OLEDs) and field-effect transistors (FETs). Recent studies have demonstrated that incorporating isoquinolin-8-amine into polymer backbones can significantly improve the charge transport properties of these materials, leading to enhanced device performance.

Another promising application of isoquinolin-8-amine lies in its use as a building block for bioactive molecules. In medicinal chemistry, this compound has been employed as a scaffold for designing potential drug candidates targeting various diseases, including cancer and neurodegenerative disorders. For example, researchers have reported that certain isoquinolinyl amine derivatives exhibit potent anti-proliferative activity against cancer cell lines, suggesting their potential as anti-cancer agents.

Furthermore, isoquinolin-8-amine has found utility in catalysis due to its ability to act as a ligand in transition metal complexes. These complexes have been shown to exhibit high catalytic activity in various organic transformations, such as alkene hydrogenation and cross-coupling reactions. Recent advancements in this area have focused on optimizing the ligand structure to enhance catalytic efficiency and selectivity, paving the way for its application in industrial processes.

The growing interest in isoquinolinyl amine derivatives has also led to extensive research into their electrochemical properties. Studies have shown that these compounds can serve as effective redox-active components in energy storage devices, such as supercapacitors and batteries. By modifying the substituents on the isoquinoline ring, researchers have been able to tune the redox potential and improve the overall performance of these devices.

In conclusion, isoquinolinyl amine (CAS No. 23687-27-) is a versatile compound with diverse applications across multiple disciplines. Its unique chemical properties and structural flexibility make it an invaluable tool for scientists and engineers working in areas ranging from materials science to medicinal chemistry. As research continues to uncover new functionalities and applications for this compound, its significance in both academic and industrial settings is expected to grow further.

• 23687-26-5(isoquinolin-6-amine)
• 611-34-7(quinolin-5-amine)
• 1125-60-6(isoquinolin-5-amine)
• 23707-37-1(Isoquinolin-7-amine)
• 578-68-7(quinolin-4-amine)
• 951-80-4(3,9-Acridinediamine)
• 146614-41-7(5-Aminoquinoline)
• 120546-60-3(7,8-Isoquinolinediamine)
• 152814-23-8(5-Aminoisoquinoline Hydrochloride)
• 90-45-9(9-Aminoacridine)