Cas no 141602-36-0 (4,5-Dichloro-6-(trifluoromethyl)pyrimidine)
4,5-Dichloro-6-(trifluoromethyl)pyrimidine is a halogenated pyrimidine derivative with significant utility in pharmaceutical and agrochemical synthesis. Its key structural features—two chlorine atoms and a trifluoromethyl group—enhance reactivity, making it a versatile intermediate for nucleophilic substitution and cross-coupling reactions. The electron-withdrawing trifluoromethyl group improves metabolic stability in bioactive compounds, while the dichloro substitution allows selective functionalization. This compound is particularly valuable in the development of herbicides, fungicides, and active pharmaceutical ingredients (APIs), where its robust scaffold contributes to enhanced efficacy and selectivity. High purity grades ensure consistent performance in demanding synthetic applications.
141602-36-0 structure
Product Name:4,5-Dichloro-6-(trifluoromethyl)pyrimidine
CAS No:141602-36-0
MF:C5HCl2F3N2
MW:216.976049184799
CID:1081711
Update Time:2025-10-15
4,5-Dichloro-6-(trifluoromethyl)pyrimidine Chemical and Physical Properties
Names and Identifiers
-
- 4,5-Dichloro-6-(trifluoromethyl)pyrimidine
- 4,5-dichloro-6-trifluoromethylpyrimidine
-
- Inchi: 1S/C5HCl2F3N2/c6-2-3(5(8,9)10)11-1-12-4(2)7/h1H
- InChI Key: OFSXFPPHNGJCLB-UHFFFAOYSA-N
- SMILES: ClC1=C(N=CN=C1C(F)(F)F)Cl
Computed Properties
- Exact Mass: 215.94700
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
Experimental Properties
- PSA: 25.78000
- LogP: 2.80220
4,5-Dichloro-6-(trifluoromethyl)pyrimidine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM166162-1g |
4,5-dichloro-6-(trifluoromethyl)pyrimidine |
141602-36-0 | 95% | 1g |
$745 | 2021-08-05 | |
| Apollo Scientific | PC48394-250mg |
4,5-Dichloro-6-(trifluoromethyl)pyrimidine |
141602-36-0 | 250mg |
£198.00 | 2025-02-21 | ||
| Apollo Scientific | PC48394-1g |
4,5-Dichloro-6-(trifluoromethyl)pyrimidine |
141602-36-0 | 1g |
£396.00 | 2025-02-21 | ||
| Apollo Scientific | PC48394-5g |
4,5-Dichloro-6-(trifluoromethyl)pyrimidine |
141602-36-0 | 5g |
£792.00 | 2025-02-21 | ||
| Chemenu | CM166162-1g |
4,5-dichloro-6-(trifluoromethyl)pyrimidine |
141602-36-0 | 95% | 1g |
$629 | 2023-02-18 | |
| abcr | AB598445-250mg |
4,5-Dichloro-6-(trifluoromethyl)pyrimidine; . |
141602-36-0 | 250mg |
€392.40 | 2024-07-24 | ||
| abcr | AB598445-1g |
4,5-Dichloro-6-(trifluoromethyl)pyrimidine; . |
141602-36-0 | 1g |
€744.90 | 2024-07-24 | ||
| abcr | AB598445-5g |
4,5-Dichloro-6-(trifluoromethyl)pyrimidine; . |
141602-36-0 | 5g |
€1449.80 | 2024-07-24 |
4,5-Dichloro-6-(trifluoromethyl)pyrimidine Related Literature
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Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
-
Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
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Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
-
Eunju Nam,Jiyeon Han,Sunhee Choi,Mi Hee Lim Chem. Commun., 2021,57, 7637-7640
141602-36-0 (4,5-Dichloro-6-(trifluoromethyl)pyrimidine) Related Products
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