• 1. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
• 2. Alumina coating on 5 V lithium cobalt fluorophosphate cathode material for lithium secondary batteries – synthesis and electrochemical properties?
  S. Amaresh,K. Karthikeyan,K. J. Kim,Y. S. Lee RSC Adv., 2014,4, 23107-23115
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthalenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes

6-Fluoronaphthalen-2-Amine: A Comprehensive Overview

The compound with CAS No. 13916-91-1, commonly referred to as 6-Fluoronaphthalen-2-Amine, is a fascinating organic compound that has garnered significant attention in the fields of chemistry, materials science, and pharmacology. This compound belongs to the family of naphthylamines, which are derivatives of naphthalene with an amino group attached. The presence of a fluorine atom at the 6th position of the naphthalene ring introduces unique electronic and structural properties, making 6-Fluoronaphthalen-2-Amine a valuable molecule for various applications.

Recent advancements in synthetic chemistry have enabled the efficient synthesis of 6-Fluoronaphthalen-2-Amine through a variety of methods. One prominent approach involves the fluorination of naphthalen-2-amine using electrophilic fluorination techniques. This method ensures high yields and excellent regioselectivity, which are critical for large-scale production. Researchers have also explored alternative routes, such as nucleophilic aromatic substitution and coupling reactions, to synthesize this compound. These methods not only enhance the scalability but also provide insights into the reactivity of naphthylamines under different reaction conditions.

The electronic properties of 6-Fluoronaphthalen-2-Amine make it an attractive candidate for applications in organic electronics. The fluorine atom at the 6th position introduces electron-withdrawing effects, which modulate the electronic structure of the molecule. This modulation is particularly useful in designing materials for light-emitting diodes (LEDs), organic photovoltaics (OPVs), and field-effect transistors (FETs). Recent studies have demonstrated that incorporating 6-Fluoronaphthalen-2-Amine into conjugated polymers significantly improves their charge transport properties, leading to enhanced device performance.

In the realm of pharmacology, 6-Fluoronaphthalen-2-Amine has shown potential as a lead compound for drug discovery. Its structural similarity to known bioactive compounds suggests that it could serve as a scaffold for developing new therapeutic agents. For instance, researchers have investigated its ability to interact with various biological targets, such as enzymes and receptors, which are implicated in diseases like cancer and neurodegenerative disorders. Preliminary results indicate that 6-Fluoronaphthalen-2-Amine exhibits promising bioactivity, warranting further exploration in preclinical studies.

The environmental impact of 6-Fluoronaphthalen-2-Amine is another area of growing interest. As industries increasingly prioritize sustainability, understanding the fate and toxicity of this compound in natural ecosystems becomes crucial. Recent environmental studies have focused on its degradation pathways under aerobic and anaerobic conditions. These studies reveal that 6-Fluoronaphthalen-2-Amine undergoes biodegradation via microbial activity, with the fluorine atom playing a role in stabilizing intermediates during the process. Such insights are vital for developing eco-friendly manufacturing processes and waste management strategies.

From a synthetic perspective, 6-fluoronaphthalen-2-amines have been employed as intermediates in the synthesis of more complex molecules. For example, they can be used to construct heterocyclic compounds with potential applications in catalysis and materials science. The versatility of this compound lies in its ability to undergo various transformations, such as Friedel-Crafts alkylation, Suzuki coupling, and Stille coupling reactions. These transformations enable chemists to tailor its structure for specific applications while maintaining its core functional groups.

In conclusion, 6-fluoronaphtalenamine stands out as a multifaceted compound with diverse applications across multiple disciplines. Its unique electronic properties, coupled with its versatility in synthetic chemistry, make it an invaluable tool for researchers and industry professionals alike. As ongoing research continues to uncover new insights into its behavior and potential uses, 6-fluoronaftalenamine is poised to play an increasingly important role in shaping future innovations in organic chemistry and beyond.

• 438-32-4(4-Fluoronaphthalen-1-amine)
• 62078-78-8(6-Fluoronaphthalen-1-amine)
• 76085-46-6(Benzenamine, 4-fluoro-, monolithium salt)
• 2146-07-8(Benzenamine, 4-fluoro-,hydrochloride (1:1))
• 32622-58-5(6-Chrysenamine,12-fluoro-)
• 13720-48-4(4-Fluoronaphthalen-2-amine)
• 330803-45-7(2-Naphthalenamine,3-fluoro-)
• 13720-50-8(5-Fluoronaphthalen-2-amine)
• 13720-52-0(8-fluoronaphthalen-1-amine)
• 62078-76-6(2-Naphthalenamine,7-fluoro-(9CI))