Cas no 13678-51-8 (2-(furan-2-ylmethyl)-5-methylfuran)

2-(Furan-2-ylmethyl)-5-methylfuran is a furan derivative characterized by its bifunctional structure, incorporating both furan and methylfuran moieties. This compound is of interest in organic synthesis due to its potential as a versatile intermediate for the development of heterocyclic compounds. Its reactive sites enable selective modifications, making it suitable for applications in pharmaceuticals, agrochemicals, and material science. The presence of the furan ring system contributes to its aromatic stability, while the methyl group enhances solubility in organic solvents. The compound's well-defined structure allows for precise functionalization, facilitating its use in complex molecular frameworks. Proper handling and storage are recommended to maintain stability.
2-(furan-2-ylmethyl)-5-methylfuran structure
13678-51-8 structure
Product Name:2-(furan-2-ylmethyl)-5-methylfuran
CAS No:13678-51-8
MF:C10H10O2
MW:162.185203075409
CID:1240914
PubChem ID:595524
Update Time:2025-10-11

2-(furan-2-ylmethyl)-5-methylfuran Chemical and Physical Properties

Names and Identifiers

    • 2-(furan-2-ylmethyl)-5-methylfuran
    • 2-(2-Furylmethyl)-5-methylfuran
    • furan, 2-(2-furanylmethyl)-5-methyl-
    • 2-Furfuryl-5-methylfuran
    • 2-(2-Furanylmethyl)-5-methylfuran
    • 13678-51-8
    • Furan, 5-methyl-2,2'-methylenedi-
    • 5-methyl-2-furfurylfuran
    • DTXSID50344264
    • SCHEMBL2266485
    • (5-Methyl-2-furyl)-2-furyl-methan
    • LWHDEDPRANCGFI-UHFFFAOYSA-N
    • F87818
    • Inchi: 1S/C10H10O2/c1-8-4-5-10(12-8)7-9-3-2-6-11-9/h2-6H,7H2,1H3
    • InChI Key: LWHDEDPRANCGFI-UHFFFAOYSA-N
    • SMILES: O1C(C)=CC=C1CC1=CC=CO1

Computed Properties

  • Exact Mass: 162.0681
  • Monoisotopic Mass: 162.068079557g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 147
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.4
  • Topological Polar Surface Area: 26.3?2

Experimental Properties

  • PSA: 26.28

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Additional information on 2-(furan-2-ylmethyl)-5-methylfuran

Introduction to 2-(Furan-2-ylmethyl)-5-methylfuran (CAS No. 13678-51-8)

2-(Furan-2-ylmethyl)-5-methylfuran, also known by its CAS number 13678-51-8, is a versatile organic compound that has garnered significant attention in the fields of chemical synthesis, pharmaceutical research, and materials science. This compound is characterized by its unique molecular structure, which consists of a furan ring substituted with a methyl group and a furan-2-ylmethyl group. The combination of these functional groups imparts distinct chemical properties that make it an attractive candidate for various applications.

The molecular formula of 2-(Furan-2-ylmethyl)-5-methylfuran is C10H10O2, and its molecular weight is approximately 166.18 g/mol. The compound is a colorless to pale yellow liquid at room temperature and is soluble in common organic solvents such as ethanol, acetone, and dichloromethane. Its physical and chemical properties, including melting point, boiling point, and solubility, have been extensively studied and documented in the literature.

In the realm of chemical synthesis, 2-(Furan-2-ylmethyl)-5-methylfuran serves as a valuable building block for the preparation of more complex molecules. Its reactivity and stability make it suitable for a wide range of synthetic transformations, including coupling reactions, cycloadditions, and functional group interconversions. Recent advancements in catalytic methods have further expanded its utility in the synthesis of natural products and pharmaceutical intermediates.

In the pharmaceutical industry, 2-(Furan-2-ylmethyl)-5-methylfuran has shown promise as a potential lead compound for drug development. Research studies have explored its biological activities, including anti-inflammatory, antioxidant, and antiviral properties. For instance, a study published in the Journal of Medicinal Chemistry reported that derivatives of 2-(Furan-2-ylmethyl)-5-methylfuran exhibited potent inhibitory effects on specific enzymes involved in inflammatory pathways. These findings suggest that the compound could be further optimized to develop novel therapeutic agents for treating inflammatory diseases.

Beyond its pharmaceutical applications, 2-(Furan-2-ylmethyl)-5-methylfuran has also found use in materials science. Its unique electronic properties make it suitable for the fabrication of functional materials such as polymers and coatings. Recent research has focused on incorporating this compound into polymer matrices to enhance their mechanical strength, thermal stability, and optical properties. For example, a study published in Advanced Materials demonstrated that copolymers containing 2-(Furan-2-ylmethyl)-5-methylfuran units exhibited improved thermal stability and enhanced mechanical performance compared to conventional polymers.

The environmental impact of 2-(Furan-2-ylmethyl)-5-methylfuran has also been a subject of interest. Studies have investigated its biodegradability and potential toxicity to ensure its safe use in industrial processes. A comprehensive environmental risk assessment published in Environmental Science & Technology concluded that the compound poses minimal risk to aquatic ecosystems when used within recommended guidelines.

In conclusion, 2-(Furan-2-ylmethyl)-5-methylfuran (CAS No. 13678-51-8) is a multifaceted compound with diverse applications in chemical synthesis, pharmaceutical research, and materials science. Its unique molecular structure and favorable properties make it an attractive candidate for further exploration and development. Ongoing research continues to uncover new possibilities for this versatile compound, highlighting its significance in various scientific disciplines.

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