Cas no 131002-02-3 (Benzamide, 2-bromo-5-chloro-)

Benzamide, 2-bromo-5-chloro-, is a halogenated aromatic compound featuring both bromo and chloro substituents on the benzene ring. Its distinct molecular structure makes it a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. The presence of halogen groups enhances its reactivity in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the construction of complex molecular frameworks. This compound exhibits high purity and stability under standard conditions, ensuring reliable performance in synthetic applications. Its well-defined chemical properties and versatility in functionalization make it a preferred choice for researchers in medicinal chemistry and materials science.
Benzamide, 2-bromo-5-chloro- structure
Benzamide, 2-bromo-5-chloro- structure
Product Name:Benzamide, 2-bromo-5-chloro-
CAS No:131002-02-3
MF:C7H5BrClNO
MW:234.477699995041
CID:3706431
PubChem ID:15111013
Update Time:2025-06-14

Benzamide, 2-bromo-5-chloro- Chemical and Physical Properties

Names and Identifiers

    • Benzamide, 2-bromo-5-chloro-
    • STL412003
    • 2-bromo-5-chlorobenzamide
    • 131002-02-3
    • SCHEMBL24821886
    • DTXSID101312330
    • AKOS000297757
    • Inchi: 1S/C7H5BrClNO/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,(H2,10,11)
    • InChI Key: MUPYRHASLDDKJT-UHFFFAOYSA-N
    • SMILES: C(N)(=O)C1=CC(Cl)=CC=C1Br

Computed Properties

  • Exact Mass: 232.92430Da
  • Monoisotopic Mass: 232.92430Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 165
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.1
  • Topological Polar Surface Area: 43.1?2

Benzamide, 2-bromo-5-chloro- Pricemore >>

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Additional information on Benzamide, 2-bromo-5-chloro-

Comprehensive Overview of Benzamide, 2-bromo-5-chloro- (CAS No. 131002-02-3): Properties, Applications, and Industry Insights

Benzamide, 2-bromo-5-chloro- (CAS No. 131002-02-3) is a halogenated aromatic compound widely recognized for its versatile applications in pharmaceutical intermediates, agrochemical synthesis, and material science. With the rising demand for halogenated benzamide derivatives, this compound has garnered significant attention due to its unique molecular structure, characterized by bromine and chlorine substituents at the 2- and 5-positions of the benzamide ring. Researchers and industry professionals frequently search for terms like "2-bromo-5-chlorobenzamide uses" or "CAS 131002-02-3 suppliers," reflecting its commercial and scientific relevance.

The compound's physicochemical properties include a molecular weight of 234.48 g/mol, a crystalline solid form, and moderate solubility in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. Its stability under controlled conditions makes it suitable for fine chemical synthesis, particularly in the development of bioactive molecules. Recent studies highlight its role as a precursor in the synthesis of antimicrobial agents and herbicides, aligning with global trends in sustainable agriculture and drug discovery.

In the pharmaceutical sector, Benzamide, 2-bromo-5-chloro- is often explored for its potential in kinase inhibitor development, a hot topic in oncology research. Searches for "halogenated benzamides in drug design" have surged, driven by the need for targeted therapies. Additionally, its application in polymer modification and liquid crystal technology addresses growing interest in advanced materials for electronics and optics.

From an industrial perspective, the compound's synthesis typically involves palladium-catalyzed cross-coupling or electrophilic aromatic substitution, methods frequently queried in academic and patent literature. Environmental and regulatory considerations are also critical, with users searching for "green synthesis of 2-bromo-5-chlorobenzamide" to align with green chemistry principles.

In summary, Benzamide, 2-bromo-5-chloro- (CAS No. 131002-02-3) exemplifies the intersection of innovation and practicality, serving as a cornerstone in multiple high-growth industries. Its adaptability to emerging technologies and compliance with sustainability goals ensure its continued prominence in scientific and industrial discourse.

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