• 1. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
• 2. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?
  Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
• 3. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
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• 4. Excimer formation effects and trap-assisted charge recombination loss channels in organic solar cells of perylene diimide dimer acceptors?
  Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
• 5. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives

Comprehensive Overview of 3-(4-Carboxyphenyl)-5-methoxybenzoic acid (CAS No. 1261931-39-8): Properties, Applications, and Industry Insights

3-(4-Carboxyphenyl)-5-methoxybenzoic acid (CAS No. 1261931-39-8) is a specialized organic compound gaining attention in pharmaceutical and materials science research. This dicarboxylic acid derivative features a unique molecular structure combining methoxy and carboxyl functional groups, making it valuable for drug intermediate synthesis and polymeric material development. Recent studies highlight its potential as a building block for advanced biocompatible polymers, aligning with the growing demand for sustainable materials in medical applications.

The compound's dual carboxyl groups enable versatile chemical modifications, particularly in creating pH-sensitive drug delivery systems—a hot topic in targeted cancer therapy research. Analytical data shows its water solubility (23 mg/mL at 25°C) and thermal stability (decomposition at 285°C) make it suitable for bioconjugation processes. Industry reports indicate a 17% annual growth in demand for such multifunctional aromatic acids, driven by personalized medicine advancements and green chemistry initiatives.

In material science, 3-(4-Carboxyphenyl)-5-methoxybenzoic acid serves as a precursor for liquid crystal polymers (LCPs) used in flexible electronics—a sector projected to reach $48 billion by 2027. Its rigid-rod molecular structure contributes to exceptional mechanical strength in composite materials, addressing industry needs for lightweight automotive components. Chromatographic studies confirm ≥98% purity in commercial batches, meeting GMP standards for pharmaceutical applications.

Environmental considerations position this compound favorably, as its biodegradation pathway produces non-toxic metabolites—a critical factor in EPA-approved chemicals. Recent patent filings (2022-2023) reveal novel applications in OLED materials and self-healing coatings, with researchers leveraging its electron-withdrawing properties to enhance charge transport efficiency. The global market for such high-performance intermediates is expected to grow at 6.8% CAGR through 2030.

Quality control protocols for CAS 1261931-39-8 typically involve HPLC-UV analysis (λ=254 nm) and FT-IR spectroscopy to verify the characteristic carbonyl stretching at 1685 cm?1. Suppliers increasingly provide REACH-compliant documentation, responding to stringent EU chemical regulations. Academic interest is evidenced by 42 peer-reviewed publications since 2018, particularly exploring its metal-organic framework (MOF) formation capabilities for gas storage applications.

Emerging applications include its use in bioimaging probes, where the methoxy group enhances fluorescence quantum yield by 32% compared to non-substituted analogs. Process chemistry innovations have reduced synthesis byproducts to <0.5%, addressing industrial scalability challenges. The compound's logP value of 1.2 suggests favorable blood-brain barrier permeability, sparking neuroscience research into neurodegenerative disease treatments.

• 168618-45-9(3'-Methoxy1,1'-biphenyl-3-carboxylic Acid)
• 1261939-24-5(5-Methoxy-3-(4-methoxyphenyl)benzoic acid)
• 5783-36-8(3'-methoxy-1,1'-biphenyl-4-carboxylic acid)
• 1261905-12-7(3-(3-Carboxyphenyl)-5-methoxybenzoic acid)
• 1261914-44-6(5-Methoxy-3-(3-methylphenyl)benzoic acid)
• 725-05-3(4'-Methoxybiphenyl-3-carboxylic acid)
• 725-14-4(4-(4-Methoxyphenyl)benzoic acid)
• 1261889-23-9(5-Methoxy-3-(4-methylphenyl)benzoic acid)
• 1215205-54-1(3'-Methoxy-5'-methylbiphenyl-3-carboxylic acid)
• 1215205-86-9(3',5'-Dimethoxybiphenyl-3-carboxylic acid)