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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolopyridines Pyrrolopyridines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolopyridines

Comprehensive Overview of 1H-Pyrrolo[3,2-c]pyridine-3-carbonitrile (CAS No. 1260385-57-6)

1H-Pyrrolo[3,2-c]pyridine-3-carbonitrile (CAS No. 1260385-57-6) is a heterocyclic organic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural properties. This compound belongs to the pyrrolopyridine family, a class of nitrogen-containing bicyclic structures known for their versatility in drug discovery. The presence of both pyrrole and pyridine rings in its backbone makes it a valuable scaffold for designing bioactive molecules, particularly in the development of kinase inhibitors and antimicrobial agents.

In recent years, the demand for 1H-Pyrrolo[3,2-c]pyridine-3-carbonitrile has surged, driven by its potential applications in treating diseases such as cancer and inflammatory disorders. Researchers are particularly interested in its carbonitrile functional group, which enhances binding affinity to biological targets. This compound is often explored in high-throughput screening (HTS) assays, where its reactivity and stability under physiological conditions make it a preferred candidate for lead optimization. Additionally, its low molecular weight and high solubility in organic solvents facilitate its use in combinatorial chemistry.

The synthesis of 1H-Pyrrolo[3,2-c]pyridine-3-carbonitrile typically involves multi-step reactions, including cyclization and nitrile introduction. Advanced techniques such as microwave-assisted synthesis and catalyzed cross-coupling have been employed to improve yield and purity. These methods align with the growing trend of green chemistry, minimizing waste and energy consumption. The compound’s CAS No. 1260385-57-6 is frequently searched in scientific databases, reflecting its relevance in medicinal chemistry and material science.

From a commercial perspective, 1H-Pyrrolo[3,2-c]pyridine-3-carbonitrile is supplied by specialized chemical vendors catering to the pharmaceutical industry. Its pricing and availability are influenced by factors such as scale-up challenges and regulatory compliance. Companies investing in this compound often prioritize GMP-grade production to meet stringent quality standards. Furthermore, its inclusion in patent filings highlights its intellectual property value, particularly in novel drug formulations targeting orphan diseases.

Beyond therapeutics, 1H-Pyrrolo[3,2-c]pyridine-3-carbonitrile is investigated for its role in organic electronics. Its conjugated system and electron-withdrawing nitrile group make it a candidate for OLEDs and photovoltaic devices. This dual applicability underscores its importance in interdisciplinary research. As the scientific community continues to explore its potential, CAS No. 1260385-57-6 remains a focal point for innovation in both life sciences and advanced materials.

In summary, 1H-Pyrrolo[3,2-c]pyridine-3-carbonitrile exemplifies the convergence of chemistry and biology, offering solutions to some of today’s most pressing challenges. Its structural modularity and diverse applications ensure its prominence in future research endeavors, making it a compound worth watching in the evolving landscape of small molecule therapeutics and functional materials.

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• 5457-28-3(1H-indole-3-carbonitrile)
• 194490-13-6(1H-Indole-3-carbonitrile,5-methyl-)
• 34846-64-5(quinoline-3-carbonitrile)
• 25957-69-1(1H-Pyrrolo[2,3-c]pyridine-3-carbonitrile)
• 74316-57-7(5-Quinolinecarbonitrile, 8-methyl-)
• 194490-22-7(1H-Indole-3-carbonitrile,7-methyl-)
• 194490-23-8(6-methyl-1H-Indole-3-carbonitrile)