Cas no 121282-70-0 (tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate)

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate structure
121282-70-0 structure
Product Name:tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate
CAS No:121282-70-0
MF:C11H21NO3
MW:215.289343595505
MDL:MFCD04974283
CID:133294
PubChem ID:10921888
Update Time:2024-11-03

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl (trans-2-hydroxycyclohexyl)carbamate
    • Carbamic acid,N-[(1R,2R)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester, rel-
    • tert-butyl 2-hydroxycyclohexylcarbamate
    • (+/-)-trans-(1-pyrrolidinyl)cyclopentan-2-ol
    • (1R,2R)-2-(pyrrolidin-1-yl)cyclopentan-1-ol
    • (1S,2S)-1-hydroxy-2-tert-butoxycarbonylamino-cyclohexane
    • (1S,2S)-2
    • (1S,2S)-2-tert-Butoxycarbonylamino-1-cyclohexanol
    • 2-(pyrrolidin-1-yl)cyclopentanol
    • AK-95886
    • KB-61863
    • RL03170
    • SBB051145
    • tert-butyl (1S,2S)-N-(2-hydroxycyclohexyl)carbamate
    • trans-2-(pyrrolidin-1-yl)cyclopentanol
    • trans-2-(tert-Butoxycarbonylamino)-cyclohexanol
    • 1R,2R-Boc-2-aMinocyclohexanol
    • trans-N-Boc-2-aminocyclohexanol
    • tert-Butyl (trans-2-hydroxycyclohexyl)
    • tert-butyl (2-hydroxycyclohexyl)carbaMate
    • tert-butyl (1R,2R)-2-hydroxycyclohexylcarbamate
    • Boc-(+/-)-trans-2-aminocyclohexanol
    • tert-butyl ((1R,2R)-2-hydroxycyclohexyl)carbamate
    • (1R,2R)-trans-N-Boc-2-aminocyclohexanol
    • tert-butyl N-[(1R,2R)-2-hydroxycyclohexyl]carbamate
    • trans-1-(Boc-Amino)-2-hydroxycyclohexane
    • trans-2-(Boc-amino)cyclohexanol
    • PubChem19549
    • XVROWZPERFUOCE-RKDXNWHRSA-N
    • tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate
    • EN300-154306
    • Carbamic acid, N-[(1R,2R)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester
    • tert-butyl(1R,2R)-2-hydroxycyclohexylcarbamate
    • AKOS015911497
    • A850192
    • EN300-1272081
    • SCHEMBL1670964
    • racemic (trans-2-Hydroxy-cyclohexyl)-carbamic acid tert-butyl ester
    • 155975-19-2
    • racemic trans-(2-hydroxy-cyclohexyl)-carbamic acid tert-butyl ester
    • rac-tert-butyl N-[(1R,2R)-2-hydroxycyclohexyl]carbamate
    • (1R,2R) (2-Hydroxycyclohexyl)-carbamic acid tert-butyl ester
    • Carbamic acid, [(1R,2R)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester
    • Trans-tert-butyl 2-hydroxycyclohexyl)carbamate
    • (1R,2R)-1-(Boc-Amino)-2-hydroxycyclohexane
    • J-524324
    • 121282-70-0
    • (1R, 2R)-N-tert-Butoxycarbonyl-2-hydroxycyclohexylamine
    • CS-0058568
    • A883606
    • DS-3672
    • tert-butyl((1R,2R)-2-hydroxycyclohexyl)carbamate
    • AM9705
    • trans-tert-butyl 2-hydroxycyclohexylcarbamate
    • P15625
    • (1R,2R)-trans-N-Boc-2-aminocyclohexanol, >=95.0% (GC)
    • (1R,2R)-N-Boc-2-Aminocyclohexanol
    • tert-Butyl (1R,2R)-2-hydroxycyclohexyl;trans-2-(Boc-amino)cyclohexanol
    • MFCD11656036
    • MFCD04974283
    • Carbamic acid, (2-hydroxycyclohexyl)-, 1,1-dimethylethyl ester, trans- (ZCI)
    • Carbamic acid, [(1R,2R)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester, rel- (9CI)
    • rel-1,1-Dimethylethyl N-[(1R,2R)-2-hydroxycyclohexyl]carbamate (ACI)
    • MDL： MFCD04974283
    • Inchi： 1S/C11H21NO3/c1-11(2,3)15-10(14)12-8-6-4-5-7-9(8)13/h8-9,13H,4-7H2,1-3H3,(H,12,14)/t8-,9-/m1/s1
    • InChI Key： XVROWZPERFUOCE-RKDXNWHRSA-N
    • SMILES： O[C@@H]1CCCC[C@H]1NC(=O)OC(C)(C)C

Computed Properties

  • Exact Mass: 215.15214353g/mol
  • Monoisotopic Mass: 215.15214353g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 222
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 58.6
  • XLogP3: 1.6

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate Security Information

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM116671-10g
trans-2-(Boc-amino)cyclohexanol
 121282-70-0 95%
10g
 $280 2021-06-15
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-WD795-50mg
tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate
 121282-70-0 97%
50mg
 56.0CNY 2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-WD795-200mg
tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate
 121282-70-0 97%
200mg
 135.0CNY 2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-WD795-1g
tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate
 121282-70-0 97%
1g
 372.0CNY 2021-07-12
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
B845819-250mg
tert-Butyl (trans-2-hydroxycyclohexyl)carbamate
 121282-70-0 97%
250mg
 ￥98.00 2022-09-29
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
B845819-1g
tert-Butyl (trans-2-hydroxycyclohexyl)carbamate
 121282-70-0 97%
1g
 ￥246.00 2022-09-29
abcr
AB436203-250 mg
tert-Butyl (trans-2-hydroxycyclohexyl)carbamate; .
 121282-70-0
250mg
 €93.80 2023-04-23
abcr
AB436203-1 g
tert-Butyl (trans-2-hydroxycyclohexyl)carbamate; .
 121282-70-0
1g
 €140.00 2023-04-23
abcr
AB436203-5 g
tert-Butyl (trans-2-hydroxycyclohexyl)carbamate; .
 121282-70-0
5g
 €290.50 2023-04-23
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
B845819-5g
tert-Butyl (trans-2-hydroxycyclohexyl)carbamate
 121282-70-0 97%
5g
 ￥913.00 2022-09-29

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Triethylamine ,  Palladium Solvents: Ethyl acetate ;  overnight, rt
Reference
Intramolecular azide-alkyne [3 + 2] cycloaddition: versatile route to new heterocyclic structural scaffolds
Li, Rongti; Jansen, Daniel J.; Datta, Apurba, Organic & Biomolecular Chemistry, 2009, 7(9), 1921-1930

Production Method 2

Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethyl acetate
Reference
One-pot transformation of the azido-group to the N-(tert-butoxycarbonyl)amino group
Saito, Seiki; Nakajima, Hitoshi; Inaba, Masami; Moriwake, Toshio, Tetrahedron Letters, 1989, 30(7), 837-8

Production Method 3

Reaction Conditions
1.1 Reagents: Sodium hydride Solvents: Tetrahydrofuran ;  1.5 h, reflux
1.2 4 h, rt
Reference
Synthesis of annulated 1,4-dioxanes and perhydro-1,4-oxazines by domino-Wacker-carbonylation and domino-Wacker-Mizoroki-Heck reactions
Tietze, Lutz F.; Heins, Arne; Soleiman-Beigi, Mohammad; Raith, Christian, Heterocycles, 2009, 77(2), 1123-1146

Production Method 4

Reaction Conditions
1.1 Reagents: Ammonia Solvents: Methanol ,  Water ;  rt
1.2 Solvents: Dichloromethane ;  rt; 1 h, rt
Reference
Thermal Safety and Structure-Related Reactivity Investigation of Five-Membered Cyclic Sulfamidates
Ferrari, Thomas ; Blum, Caitlin ; Amini-Rentsch, Lara; Brodard, Pierre; Dabros, Michal ; et al, Organic Process Research & Development, 2022, 26(9), 2614-2623

Production Method 5

Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Dichloromethane
Reference
Novel Enantiopure β-Amino Alcohols and β-Amino Thiols in Asymmetric Catalysis
Rantanen, Toni, 2007, , ,

Production Method 6

Reaction Conditions
1.1 Reagents: Trimethylphosphine Solvents: Tetrahydrofuran
1.2 Reagents: Sodium hydroxide Solvents: Water
1.3 Solvents: Tetrahydrofuran
Reference
From vicinal azido alcohols to Boc-amino alcohols or oxazolidinones, with trimethylphosphine and Boc2O or CO2
Ariza, X.; Pineda, O.; Urpi, F.; Vilarrasa, J., Tetrahedron Letters, 2001, 42(30), 4995-4999

Production Method 7

Reaction Conditions
1.1 Catalysts: Iodine ;  5 min, rt
Reference
Revisiting Iodine-Mediated N-tert-Butoxycarbonylation of Amines
Murthia, Ponugubati R. K.; Kumar, Gondrala P.; Rambabua, Dandela; Rao, Mandava V. B.; Pal, Manojit, Current Catalysis, 2014, 3(1), 47-52

Production Method 8

Reaction Conditions
1.1 Reagents: Zinc ,  Ammonium chloride Solvents: Methanol ;  15 min, 0 °C; 10 min, 0 °C
1.2 0 °C → rt
Reference
An efficient reduction protocol for the synthesis of β-hydroxycarbamates from β-nitro alcohols in one pot: a facile synthesis of (-)-β-conhydrine
Saikia, Partha Pratim; Baishya, Gakul; Goswami, Abhishek; Barua, Nabin C., Tetrahedron Letters, 2008, 49(46), 6508-6511

Production Method 9

Reaction Conditions
1.1 Solvents: Methanol ;  rt
Reference
Discovery of novel hydantoins as selective non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)
Sheppeck, James E.; Gilmore, John L.; Yang, Anle; Chen, Xiao-Tao; Xue, Chu-Biao; et al, Bioorganic & Medicinal Chemistry Letters, 2007, 17(5), 1413-1417

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate Raw materials

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate Preparation Products

tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate Related Literature

Related Categories

121282-70-0 (tert-butyl N-[trans-2-hydroxycyclohexyl]carbamate) Related Products

Recommended suppliers
SunaTech Inc.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
SunaTech Inc.
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Xinsu New Materials Co., Ltd
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhejiang Brunova Technology Co., Ltd.
HANGZHOU BAIS CHEMICAL TECHNOLOGY CO., LTD.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
HANGZHOU BAIS CHEMICAL TECHNOLOGY CO., LTD.
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.