Cas no 1211587-33-5 (2-(1H-pyrazol-1-yl)pyrimidin-5-amine)
2-(1H-Pyrazol-1-yl)pyrimidin-5-amine is a heterocyclic compound featuring a pyrazole-pyrimidine hybrid structure, which exhibits significant potential in medicinal chemistry and materials science. The presence of both pyrazole and pyrimidine rings confers unique electronic properties, making it a versatile intermediate for synthesizing bioactive molecules, particularly kinase inhibitors and anticancer agents. Its amine functionality at the 5-position allows for further derivatization, enabling the introduction of diverse substituents to fine-tune pharmacological activity. The compound's rigid, planar structure enhances binding affinity to biological targets, while its moderate polarity ensures favorable solubility for drug formulation. Its synthetic accessibility and structural modularity make it a valuable scaffold for developing novel therapeutic candidates and functional materials.
1211587-33-5 structure
Product Name:2-(1H-pyrazol-1-yl)pyrimidin-5-amine
CAS No:1211587-33-5
MF:C7H7N5
MW:161.163979768753
CID:5735051
PubChem ID:49758821
Update Time:2025-07-02
2-(1H-pyrazol-1-yl)pyrimidin-5-amine Chemical and Physical Properties
Names and Identifiers
-
- 5-Amino-2-(1H-pyrazol-1-yl)pyrimidine
- 5-Pyrimidinamine, 2-(1H-pyrazol-1-yl)-
- 2-(1h-pyrazol-1-yl)pyrimidin-5-amine
- 1211587-33-5
- 2-pyrazol-1-ylpyrimidin-5-amine
- AKOS010387238
- F1912-0311
- 2-(1H-pyrazol-1-yl)pyrimidin-5-amine
-
- Inchi： 1S/C7H7N5/c8-6-4-9-7(10-5-6)12-3-1-2-11-12/h1-5H,8H2
- InChI Key： WSBRRUMBUYFLCL-UHFFFAOYSA-N
- SMILES： N1(C=CC=N1)C1N=CC(=CN=1)N
Computed Properties
- Exact Mass: 161.07014524g/mol
- Monoisotopic Mass: 161.07014524g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
- Complexity: 143
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: -0.2
- Topological Polar Surface Area: 69.6?2
2-(1H-pyrazol-1-yl)pyrimidin-5-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | H165646-100mg |
2-(1h-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 100mg |
$ 115.00 | 2022-06-04 | ||
| TRC | H165646-500mg |
2-(1h-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 500mg |
$ 475.00 | 2022-06-04 | ||
| TRC | H165646-1g |
2-(1h-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 1g |
$ 730.00 | 2022-06-04 | ||
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1632373-250mg |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 98% | 250mg |
￥6916.00 | 2024-08-09 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1632373-500mg |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 98% | 500mg |
￥13822.00 | 2024-08-09 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1632373-1g |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 98% | 1g |
￥19135.00 | 2024-08-09 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1632373-2.5g |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 98% | 2.5g |
￥29019.00 | 2024-08-09 | |
| Life Chemicals | F1912-0311-0.25g |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 95%+ | 0.25g |
$486.0 | 2023-09-06 | |
| Life Chemicals | F1912-0311-0.5g |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 95%+ | 0.5g |
$512.0 | 2023-09-06 | |
| Life Chemicals | F1912-0311-1g |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine |
1211587-33-5 | 95%+ | 1g |
$539.0 | 2023-09-06 |
2-(1H-pyrazol-1-yl)pyrimidin-5-amine Related Literature
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José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
-
Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
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P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
-
Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
-
Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha Rao Green Chem., 2017,19, 4446-4450
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