Production Method 1

930-27-8

120-92-3

930-18-7

625-33-2

Reaction Conditions

1.1 Reagents: Hydrogen ;  2 MPa, 600 °C

Reference

Understanding cellulose pyrolysis under hydrogen atmosphere

Li, Tan; Miao, Kai; Zhao, Zhigang; Li, Yuqing; Wang, Huiyuan; et al, Energy Conversion and Management, 2022, 254,

Production Method 2

8068-05-1

120-92-3

496-16-2

876-02-8

90-00-6

93-51-6

608-43-5

39151-19-4

6443-69-2

90-05-1

96-39-9

2758-18-1

105-38-4

27129-87-9

5912-86-7

30434-64-1

2785-89-9

Reaction Conditions

1.1 250 h

Reference

Catalytic pyrolysis of lignin over hierarchical HZSM 5 zeolites prepared by post-treatment with alkaline solutions

Tang, Songshan; et al, Journal of Analytical and Applied Pyrolysis, 2019, 137, 86-95

Cyclopentanone Raw materials

• 3-Methylfuran
• Sulfate Lignin

Cyclopentanone Preparation Products

• Coumaran (496-16-2)
• 4'-Hydroxy-3'-methylacetophenone (876-02-8)
• 2-Ethylphenol (90-00-6)
• 2-Methoxy-4-methylphenol (93-51-6)
• 2,3-Xylohydroquinone (608-43-5)
• 3′,5′-Dimethoxyacetophenone (39151-19-4)
• 3,4,5-Trimethoxytoluene (6443-69-2)
• Cyclopropane,1,2-dimethyl-, (1R,2S)-rel- (930-18-7)
• Guaiacol (90-05-1)
• 3-Penten-2-one (625-33-2)
• 1-methylcyclopenta-1,3-diene (96-39-9)
• 3-methylcyclopent-2-en-1-one (2758-18-1)
• Vinyl Propionate (stabilized with MEHQ) (105-38-4)
• 3,5-Dimethylbenzyl alcohol (27129-87-9)
• Cyclopentanone (120-92-3)
• Phenol,2-methoxy-4-(1Z)-1-propen-1-yl- (5912-86-7)
• 2-Cyclopenten-1-one,3,4-dimethyl- (30434-64-1)
• 4-Ethylguaiacol (2785-89-9)

• 1. Liquid phase behaviour of 1-butyl-3-methylimidazolium 2-(2-methoxyethoxy)-ethylsulfate with organic solvents and water
  Urszula Domańska,Andrzej Marciniak Green Chem. 2007 9 262
• 2. Synthesis of renewable C–C cyclic oxygenated compounds dedicated for high-density biofuels from biomass-derived cyclopentanone
  Li Bai,Lulu Chen,Mei Wu,Ke Song,Xianwu Zhou,Jie Guo,Hu Pan,Shima Liu,Jian He New J. Chem. 2023 47 8111
• 3. Efficient synthesis of C15 fuel precursor by heterogeneously catalyzed aldol-condensation of furfural with cyclopentanone
  Lei Ao,Wei Zhao,Yin-shuang Guan,Ding-kai Wang,Kai-shuai Liu,Tian-tian Guo,Xing Fan,Xian-yong Wei RSC Adv. 2019 9 3661
• 4. Synthesis of C15 and C10 fuel precursors with cyclopentanone and furfural derived from hemicellulose
  Wei Wang,Xiaohui Ji,Hongguang Ge,Zhizhou Li,Guanghui Tian,Xianzhao Shao,Qiang Zhang RSC Adv. 2017 7 16901
• 5. Enantioselective copper catalysed intramolecular C–H insertion reactions of α-diazo-β-keto sulfones, α-diazo-β-keto phosphine oxides and 2-diazo-1,3-diketones; the influence of the carbene substituent
  Amy E. Shiely,Catherine N. Slattery,Alan Ford,Kevin S. Eccles,Simon E. Lawrence,Anita R. Maguire Org. Biomol. Chem. 2017 15 2609

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Cyclic ketones
• Pesticide Chemicals Pesticide Active Ingredients Standard Substances
• Solvents and Organic Chemicals Organic Compounds Acids/Esters
• Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone
• Natural Products and Extracts Flavors and Fragrances
• Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients

Cyclopentanone (CAS No: 120-92-3) in Modern Chemical and Pharmaceutical Research

Cyclopentanone, with the chemical formula C₅H₈O, is a cyclic ketone that has garnered significant attention in the fields of organic synthesis, pharmaceutical development, and material science. Its unique structural properties make it a versatile intermediate in the synthesis of various bioactive compounds. The compound, identified by its CAS number 120-92-3, is widely recognized for its role in producing fine chemicals and pharmaceutical intermediates. This article explores the latest advancements and applications of Cyclopentanone in contemporary research.

The chemical structure of Cyclopentanone consists of a five-membered ring with a ketone functional group. This configuration allows for diverse chemical reactions, making it a valuable building block in synthetic chemistry. The compound exhibits moderate solubility in water and common organic solvents, which enhances its utility in various chemical processes. Recent studies have highlighted its importance in the development of novel drugs and agrochemicals, where it serves as a precursor for more complex molecules.

In pharmaceutical research, Cyclopentanone has been extensively studied for its potential as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its derivatives have shown promise in treating neurological disorders, infectious diseases, and inflammatory conditions. For instance, researchers have explored its role in developing nonsteroidal anti-inflammatory drugs (NSAIDs) and antiviral agents. The ability of Cyclopentanone to undergo various functional group transformations makes it an attractive candidate for drug discovery programs.

One of the most notable applications of Cyclopentanone is in the field of polymer chemistry. It serves as a monomer or co-monomer in the synthesis of polyesters and polyamides, which are used in high-performance materials. These polymers exhibit excellent mechanical strength, thermal stability, and chemical resistance, making them suitable for aerospace, automotive, and electronics industries. Recent advancements in polymer science have demonstrated the potential of incorporating Cyclopentanone-based monomers to develop sustainable and biodegradable materials.

The industrial production of Cyclopentanone primarily involves catalytic hydrogenation of cyclopentene or oxidation of cyclopentane derivatives. Advances in catalytic systems have improved the efficiency and selectivity of these processes, reducing waste generation and energy consumption. Researchers are now focusing on green chemistry approaches to optimize the synthesis of Cyclopentanone, ensuring minimal environmental impact while maintaining high yields.

In recent years, computational chemistry has played a pivotal role in understanding the reactivity and properties of Cyclopentanone. Molecular modeling techniques have enabled scientists to predict reaction pathways and optimize synthetic routes with greater precision. These computational methods are particularly valuable in drug discovery, where they help identify potential lead compounds before experimental validation. The integration of machine learning algorithms has further accelerated this process, allowing for rapid screening of large chemical libraries.

The pharmacological significance of Cyclopentanone derivatives continues to evolve with new research findings. Studies have revealed their potential role in modulating enzyme activity and receptor binding, which is crucial for developing targeted therapies. For example, derivatives of Cyclopentanone have been investigated for their ability to inhibit enzymes involved in cancer progression or neurodegenerative diseases. These findings underscore the importance of continued research into this compound class.

The future prospects for Cyclopentanone are promising, with ongoing studies exploring its applications in renewable energy storage and carbon capture technologies. Its structural versatility allows for innovative approaches in developing advanced materials that could contribute to sustainable solutions for global challenges. As research progresses, it is expected that new methodologies will emerge to further enhance the utility and accessibility of Cyclopentanone across multiple scientific disciplines.

In conclusion, Cyclopentanone (CAS No: 120-92-3) remains a cornerstone compound in modern chemical research due to its diverse applications and structural flexibility. From pharmaceutical intermediates to advanced polymers, its contributions span multiple industries, driving innovation and sustainability. As scientists continue to uncover new possibilities with this compound, its importance is likely to grow even further.

• 3859-41-4(Cyclopentane-1,3-dione)
• 70887-60-4(Cyclopentanone, ion(1-), lithium)
• 3997-89-5(Cyclopentanone-2,2,5,5-d4)
• 4477-17-2(Cyclopentanone-d8)
• 90480-72-1(Pentanal, reaction products with cyclopentanone, dehydrated, hydrated, distn. residues)
• 36219-23-5(Cyclopentanone-β-d4)
• 90388-01-5(heptanal, reaction products with cyclopentanone, dehydrated, hydrated, distn. residues)
• 68488-80-2((CYCLOPENTANONE (1-13C) ))
• 25088-24-8(Cyclopentyl, 3-oxo-)
• 143446-05-3(Cyclopentylium, 3-oxo-)