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Introduction to 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde (CAS No. 118350-17-7)

4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde, with the CAS number 118350-17-7, is a versatile organic compound that has garnered significant attention in recent years due to its unique chemical structure and potential applications in various fields, including pharmaceuticals, materials science, and organic synthesis. This compound belongs to the class of biphenyl derivatives and is characterized by its aromatic nature and the presence of a methoxy group and an aldehyde functional group.

The molecular formula of 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde is C₁₄H₁₂O₂, and its molecular weight is 208.24 g/mol. The compound's structure consists of two phenyl rings connected by a single bond, with a methoxy group (-OCH₃) attached to the 4' position of one of the phenyl rings and an aldehyde group (-CHO) at the 3 position of the other phenyl ring. This arrangement imparts distinct chemical properties that make it a valuable intermediate in synthetic chemistry.

In the realm of pharmaceutical research, 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde has shown promise as a key intermediate in the synthesis of bioactive molecules. Recent studies have explored its potential as a precursor for the development of novel drugs targeting various diseases. For instance, researchers at the University of California, Los Angeles (UCLA) have utilized this compound in the synthesis of compounds with anti-inflammatory and anti-cancer properties. The methoxy group and the aldehyde functionality provide multiple reaction sites that can be exploited for the introduction of various functional groups, thereby expanding its utility in drug discovery.

Beyond pharmaceutical applications, 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde has also found use in materials science. Its aromatic structure and functional groups make it suitable for the synthesis of advanced materials such as polymers and liquid crystals. A study published in the Journal of Materials Chemistry A highlighted the use of this compound as a building block for creating novel liquid crystalline materials with unique optical and electronic properties. These materials have potential applications in display technologies and optoelectronic devices.

The synthetic accessibility of 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde is another factor contributing to its widespread use. Various methods have been developed for its preparation, including Suzuki coupling reactions and Grignard reactions. These synthetic routes are well-documented in the literature and can be adapted to produce high-purity samples suitable for both research and industrial applications. The ease of synthesis combined with its versatile reactivity makes it an attractive choice for chemists working on complex molecular architectures.

In terms of safety and handling, while 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde is not classified as a hazardous material under current regulations, it is important to follow standard laboratory safety protocols when working with this compound. Proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn to minimize exposure risks. Additionally, it is advisable to handle the compound in a well-ventilated area or fume hood to prevent inhalation of vapors.

The environmental impact of 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde is another consideration that researchers and manufacturers must take into account. While there are no specific environmental concerns associated with this compound at present, it is important to ensure that waste products from its synthesis and use are disposed of responsibly to minimize any potential ecological impact.

In conclusion, 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde (CAS No. 118350-17-7) is a multifaceted compound with significant potential across various scientific disciplines. Its unique chemical structure and reactivity make it an invaluable tool for synthetic chemists and researchers working on drug discovery, materials science, and other advanced applications. As ongoing research continues to uncover new possibilities for this compound, it is likely to play an increasingly important role in future scientific advancements.

• 52988-34-8(4'-methoxy-[1,1'-biphenyl]-4-carbaldehyde)
• 237069-43-1(Benzaldehyde,4-(6-methoxy-2-naphthalenyl)-)
• 342611-03-4(Benzaldehyde-formyl-d,4-(methoxy-d3)- (9CI))
• 209863-09-2(3'-Methoxy-[1,1'-biphenyl]-4-carbaldehyde)
• 19486-71-6(4-Methoxybenzaldehyde-α-d1)
• 126485-58-3(3'-methoxy-[1,1'-biphenyl]-3-carbaldehyde)
• 237069-42-0(Benzaldehyde,3-(6-methoxy-2-naphthalenyl)-)
• 95537-93-2(Anisaldehyde-13C)
• 123-11-5(p-Methoxybenzaldehyde)
• 2652-68-8(Methyl, (4-methoxyphenyl)oxo-)