Cas no 1174020-45-1 (tert-butyl (3S,4S)-4-fluoro-3-hydroxy-piperidine-1-carboxylate)

Tert-butyl (3S,4S)-4-fluoro-3-hydroxy-piperidine-1-carboxylate is a chiral piperidine derivative featuring both fluorine and hydroxyl functional groups at the 3- and 4-positions, respectively. The tert-butyloxycarbonyl (Boc) protecting group enhances stability and facilitates selective deprotection in synthetic applications. Its stereospecific (3S,4S) configuration makes it valuable for asymmetric synthesis, particularly in pharmaceutical intermediates. The fluorine substituent introduces metabolic stability and influences electronic properties, while the hydroxyl group provides a handle for further functionalization. This compound is commonly employed in medicinal chemistry for the development of bioactive molecules, leveraging its rigid piperidine scaffold and tunable reactivity. High purity and well-defined stereochemistry ensure reproducibility in research and industrial applications.
tert-butyl (3S,4S)-4-fluoro-3-hydroxy-piperidine-1-carboxylate structure
1174020-45-1 structure
Product Name:tert-butyl (3S,4S)-4-fluoro-3-hydroxy-piperidine-1-carboxylate
CAS No:1174020-45-1
MF:C10H18FNO3
MW:219.25322675705
MDL:MFCD12756120
CID:1210635
PubChem ID:45489897
Update Time:2025-05-28

tert-butyl (3S,4S)-4-fluoro-3-hydroxy-piperidine-1-carboxylate Chemical and Physical Properties

Names and Identifiers

    • 2-methyl-2-propanyl (3s,4s)-4-fluoro-3-hydroxy-1-piperidinecarbox Ylate
    • (3S,4S)-1-Boc-4-fluoro-3-piperidinol
    • tert-butyl (3S,4S)-4-fluoro-3-hydroxy-piperidine-1-carboxylate
    • 1,1-Dimethylethyl trans-3-hydroxy-4-fluoropiperidine-1-carboxylate
    • ZWB02045
    • DTXSID20670502
    • SCHEMBL1468294
    • TRANS-1-BOC-4-FLUORO-3-HYDROXYPIPERIDINE
    • MFCD12756120
    • A902587
    • (3S,4S)-tert-butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
    • 955028-82-7
    • tert-butyl (3S,4S)-4-fluoro-3-hydroxypiperidine-1-carboxylate
    • DS-8105
    • (3S,4S)-tert-butyl4-fluoro-3-hydroxypiperidine-1-carboxylate
    • 1174020-45-1
    • MFCD18425630
    • P15641
    • trans-tert-butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
    • AKOS015899092
    • (3S,4S)-1-Boc-4-fluoro-3-piperidinol ee
    • MDL： MFCD12756120
    • Inchi： 1S/C10H18FNO3/c1-10(2,3)15-9(14)12-5-4-7(11)8(13)6-12/h7-8,13H,4-6H2,1-3H3/t7-,8-/m0/s1
    • InChI Key： FZAKOAFETOZBLC-YUMQZZPRSA-N
    • SMILES： F[C@H]1CCN(C(=O)OC(C)(C)C)C[C@@H]1O

Computed Properties

  • Exact Mass: 219.12707160g/mol
  • Monoisotopic Mass: 219.12707160g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 239
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1
  • Topological Polar Surface Area: 49.8?2

tert-butyl (3S,4S)-4-fluoro-3-hydroxy-piperidine-1-carboxylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
60R1110-1g
(3S,4S)-1-Boc-4-fluoro-3-piperidinol
 1174020-45-1 98%
1g
 15943.2CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
60R1110-5g
(3S,4S)-1-Boc-4-fluoro-3-piperidinol
 1174020-45-1 98%
5g
 58345.32CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
60R1110-500mg
(3S,4S)-1-Boc-4-fluoro-3-piperidinol
 1174020-45-1 98%
500mg
 8463.46CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
60R1110-250mg
(3S,4S)-1-Boc-4-fluoro-3-piperidinol
 1174020-45-1 98%
250mg
 4655.75CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
60R1110-100mg
(3S,4S)-1-Boc-4-fluoro-3-piperidinol
 1174020-45-1 98%
100mg
 2756.14CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
60R1110-50mg
(3S,4S)-1-Boc-4-fluoro-3-piperidinol
 1174020-45-1 98%
50mg
 1797.85CNY 2021-05-07
Chemenu
CM317304-100mg
(3S,4S)-tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
 1174020-45-1 95%
100mg
 $389 2022-09-04
Chemenu
CM317304-250mg
(3S,4S)-tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
 1174020-45-1 95%
250mg
 $648 2022-09-04
Chemenu
CM317304-1g
(3S,4S)-tert-Butyl 4-fluoro-3-hydroxypiperidine-1-carboxylate
 1174020-45-1 95%
1g
 $1426 2022-09-04
eNovation Chemicals LLC
D969522-100mg
(3S,4S)-1-Boc-4-fluoro-3-piperidinol
 1174020-45-1 95%
100mg
 $455 2024-07-28

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