Cas no 1111637-74-1 (1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one)

1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-one is a halogenated pyridine derivative with significant utility in pharmaceutical and agrochemical synthesis. Its key structural features—a bromo and fluoro substituent on the pyridine ring—enhance reactivity, making it a versatile intermediate for cross-coupling reactions, nucleophilic substitutions, and further functionalization. The electron-withdrawing nature of the substituents facilitates regioselective modifications, while the ketone group offers additional derivatization potential. This compound is particularly valuable in medicinal chemistry for constructing bioactive heterocycles. High purity and stability under standard conditions ensure reliable performance in synthetic applications. Its well-defined reactivity profile supports efficient scale-up in industrial processes.
1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one structure
1111637-74-1 structure
Product Name:1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one
CAS No:1111637-74-1
MF:C7H5BrFNO
MW:218.023104429245
MDL:MFCD12024449
CID:820206
Update Time:2025-06-09

1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one Chemical and Physical Properties

Names and Identifiers

    • 1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
    • 1-(5-bromo-2-fluoro-3-pyridinyl)Ethanone
    • 1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-one
    • 1-(5-Bromo-2-fluoropyridine-3-yl)ethanone
    • NTEVXGZFBVJCAP-UHFFFAOYSA-N
    • PC7516
    • RW3178
    • FCH1409007
    • RP27092
    • AB65212
    • 3-ACETYL-5-BROMO-2-FLUOROPYRIDIN
    • 1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one
    • MDL： MFCD12024449
    • Inchi： 1S/C7H5BrFNO/c1-4(11)6-2-5(8)3-10-7(6)9/h2-3H,1H3
    • InChI Key： NTEVXGZFBVJCAP-UHFFFAOYSA-N
    • SMILES： BrC1=CN=C(C(C(C)=O)=C1)F

Computed Properties

  • Exact Mass: 216.95400
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 165
  • Topological Polar Surface Area: 30

Experimental Properties

  • Density: 1.619±0.06 g/cm3 (20 oC 760 Torr),
  • Boiling Point: 284.3±40.0 oC (760 Torr),
  • Flash Point: 125.7±27.3 oC,
  • Solubility: Slightly soluble (2.8 g/l) (25 o C),
  • PSA: 29.96000
  • LogP: 2.18580

1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one Customs Data

  • HS CODE：2933399090
  • Customs Data：

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
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SHANG HAI XIAN DING Biotechnology Co., Ltd.
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ChemScence
CS-0042075-1g
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1-(5-bromo-2-fluoropyridin-3-yl)ethan-1-one Production Method

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