Cas no 1099597-74-6 (2-chloro-6-methyl-3-(trifluoromethyl)pyridine)

2-Chloro-6-methyl-3-(trifluoromethyl)pyridine is a fluorinated pyridine derivative with significant utility in agrochemical and pharmaceutical synthesis. Its trifluoromethyl and chloro substituents enhance reactivity, making it a versatile intermediate for constructing complex molecules. The compound's electron-withdrawing groups contribute to improved stability and selectivity in cross-coupling reactions, while the methyl group offers additional functionalization potential. It is particularly valuable in the development of crop protection agents, where its structural motifs are leveraged for bioactivity. High purity and consistent quality ensure reliable performance in demanding synthetic applications. Proper handling and storage are recommended due to its halogenated nature.
2-chloro-6-methyl-3-(trifluoromethyl)pyridine structure
1099597-74-6 structure
Product Name:2-chloro-6-methyl-3-(trifluoromethyl)pyridine
CAS No:1099597-74-6
MF:C7H5ClF3N
MW:195.569511175156
MDL:MFCD11226678
CID:1189031
PubChem ID:37863457
Update Time:2025-10-28

2-chloro-6-methyl-3-(trifluoromethyl)pyridine Chemical and Physical Properties

Names and Identifiers

    • 2-chloro-6-methyl-3-(trifluoromethyl)pyridine
    • AS-43759
    • AU-004/43508206
    • 1099597-74-6
    • ZTB59774
    • DB-355922
    • 2-Chloro-6-methyl-3-(trifluoromethyl)pyridine, AldrichCPR
    • AKOS005255840
    • MFCD11226678
    • STL554754
    • SB21481
    • BBL100960
    • Pyridine, 2-?chloro-?6-?methyl-?3-?(trifluoromethyl)?-
    • 2-chloro-3-(trifluoromethyl)-6-methylpyridine
    • SCHEMBL7664844
    • CS-0313089
    • MDL: MFCD11226678
    • Inchi: 1S/C7H5ClF3N/c1-4-2-3-5(6(8)12-4)7(9,10)11/h2-3H,1H3
    • InChI Key: DIFCQOVMVHCCHY-UHFFFAOYSA-N
    • SMILES: ClC1=C(C(F)(F)F)C=CC(C)=N1

Computed Properties

  • Exact Mass: 195.0062613g/mol
  • Monoisotopic Mass: 195.0062613g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 159
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 12.9?2

2-chloro-6-methyl-3-(trifluoromethyl)pyridine Security Information

  • Hazard Category Code: 25
  • Safety Instruction: 45
  • Hazardous Material Identification: T
  • HazardClass:IRRITANT

2-chloro-6-methyl-3-(trifluoromethyl)pyridine Pricemore >>

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Additional information on 2-chloro-6-methyl-3-(trifluoromethyl)pyridine

Comprehensive Overview of 2-Chloro-6-methyl-3-(trifluoromethyl)pyridine (CAS No. 1099597-74-6)

2-Chloro-6-methyl-3-(trifluoromethyl)pyridine (CAS No. 1099597-74-6) is a specialized heterocyclic compound that has garnered significant attention in the fields of agrochemicals, pharmaceutical intermediates, and material science. This compound belongs to the pyridine derivatives family, characterized by its unique trifluoromethyl and chloro functional groups, which contribute to its reactivity and versatility in synthetic applications. Researchers and industries are increasingly exploring its potential due to its structural specificity and broad utility.

The growing demand for high-performance agrochemicals and crop protection agents has placed 2-chloro-6-methyl-3-(trifluoromethyl)pyridine in the spotlight. Its pyridine core and halogenated substituents make it a valuable building block for designing next-generation pesticides and herbicides. In particular, its trifluoromethyl group enhances the compound's lipophilicity and bioavailability, critical factors in agrochemical efficacy. Recent studies highlight its role in developing environmentally sustainable solutions, aligning with global trends toward green chemistry and reduced ecological impact.

In the pharmaceutical sector, CAS 1099597-74-6 is recognized as a key intermediate for synthesizing bioactive molecules. Its chloro and methyl substitutions offer strategic sites for further functionalization, enabling the creation of targeted therapeutics. For instance, it has been investigated in the development of central nervous system (CNS) drugs and anti-inflammatory agents. The compound's structural modularity allows researchers to tailor its properties for specific drug discovery applications, addressing unmet medical needs.

From a synthetic chemistry perspective, 2-chloro-6-methyl-3-(trifluoromethyl)pyridine serves as a versatile scaffold for cross-coupling reactions and catalyzed transformations. Its compatibility with palladium-catalyzed and copper-mediated reactions makes it a preferred choice for constructing complex heterocyclic architectures. Recent advancements in flow chemistry and microwave-assisted synthesis have further expanded its utility, reducing reaction times and improving yields.

The compound's thermal stability and solubility profile also make it suitable for material science applications. Researchers are exploring its incorporation into organic electronic materials, such as OLEDs and conductive polymers, where its electron-withdrawing properties can modulate charge transport characteristics. This aligns with the rising interest in flexible electronics and energy-efficient devices.

As the scientific community continues to investigate CAS 1099597-74-6, its role in innovative technologies and sustainable solutions is expected to grow. Whether in agrochemical formulations, pharmaceutical synthesis, or advanced materials, this compound exemplifies the intersection of chemical innovation and practical application. For researchers and industry professionals, understanding its properties and potential is essential for driving future breakthroughs.

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