Cas no 1245915-66-5 (6-Chloro-5-(trifluoromethyl)picolinaldehyde)
6-Chloro-5-(trifluoromethyl)picolinaldehyde is a versatile heterocyclic aldehyde featuring both chloro and trifluoromethyl substituents on its pyridine ring. This compound is particularly valuable in pharmaceutical and agrochemical synthesis due to its reactive aldehyde group and electron-withdrawing substituents, which enhance its utility in nucleophilic addition and condensation reactions. The trifluoromethyl group contributes to increased lipophilicity and metabolic stability, making it a useful intermediate in the development of bioactive molecules. Its well-defined structure and high purity ensure consistent performance in complex organic transformations. Suitable for use in cross-coupling reactions and as a building block for advanced intermediates, this compound offers synthetic flexibility for specialized applications.
1245915-66-5 structure
Product Name:6-Chloro-5-(trifluoromethyl)picolinaldehyde
CAS No:1245915-66-5
MF:C7H3ClF3NO
MW:209.553031206131
CID:2760503
PubChem ID:72214093
Update Time:2025-11-02
6-Chloro-5-(trifluoromethyl)picolinaldehyde Chemical and Physical Properties
Names and Identifiers
-
- AB75201
- 6-Chloro-5-(trifluoromethyl)picolinaldehyde
- 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBALDEHYDE
- 1245915-66-5
-
- Inchi: 1S/C7H3ClF3NO/c8-6-5(7(9,10)11)2-1-4(3-13)12-6/h1-3H
- InChI Key: PYBIUULFGWQDTL-UHFFFAOYSA-N
- SMILES: ClC1C(C(F)(F)F)=CC=C(C=O)N=1
Computed Properties
- Exact Mass: 208.9855259Da
- Monoisotopic Mass: 208.9855259Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 197
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.5
- Topological Polar Surface Area: 30?2
6-Chloro-5-(trifluoromethyl)picolinaldehyde Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029010673-250mg |
6-Chloro-5-(trifluoromethyl)picolinaldehyde |
1245915-66-5 | 95% | 250mg |
$980.00 | 2023-09-03 | |
| Alichem | A029010673-1g |
6-Chloro-5-(trifluoromethyl)picolinaldehyde |
1245915-66-5 | 95% | 1g |
$3068.70 | 2023-09-03 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1763563-1g |
6-Chloro-5-(trifluoromethyl)picolinaldehyde |
1245915-66-5 | 98% | 1g |
¥5458.00 | 2024-08-09 |
6-Chloro-5-(trifluoromethyl)picolinaldehyde Related Literature
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Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
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Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
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Zhizhen Lai,Mo Zhang,Jinyu Zhou,Tianjing Chen,Dan Li,Xuejing Shen,Jia Liu,Jiang Zhou,Zhili Li Analyst, 2021,146, 4261-4267
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Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
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Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
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