Cas no 1072-97-5 (5-bromopyridin-2-amine)

5-bromopyridin-2-amine is a versatile intermediate compound featuring a bromo-substituted pyridine core and an amine functional group. Its unique combination of halogenation and basicity renders it useful as a reagent in various chemical transformations, such as electrophilic aromatic substitution and catalytic reactions.

5-bromopyridin-2-amine structure

Product Name:5-bromopyridin-2-amine

CAS No:1072-97-5

MF:C₅H₅BrN₂

MW:173.010599851608

MDL:MFCD00006323

CID:40645

PubChem ID:70622

Update Time:2025-10-10

5-bromopyridin-2-amine Chemical and Physical Properties

Names and Identifiers

- 5-Bromopyridin-2-amine
- 5-bromo-2-pyridylamine
- 4-AMINO-5-CHLORO-2,1,3-BENZOTHIODIAZOLE
- 2-Amino-5-bromopyridine
- 2-Amino-5-bromopyrid
- 2-amino-5-bromo-pyridine
- 5-bromo-2-aminopyridine
- 5-Bromo-2-pyridinamine
- 5-bromopyridin-2-yl amine
- AMINO-5-BROMOPYRIDINE
- NSC 26282
- 5-BROMOPHTHALIDE
- TIMTEC-BB SBB003823
- AKOS BBS-00004444
- LABOTEST-BB LT00129606
- 2-Pyridinamine, 5-bromo-
- 5-bromopyridin-2-ylamine
- 5-bromo-pyridin-2-ylamine
- 2-amino-5-bromo pyridine
- D5QE8XW52U
- WGOLHUGPTDEKCF-UHFFFAOYSA-N
- 5-brompyridin-2-amin
- NSC26282
- PubChem1107
- 2-Amino5-bromopyridine
- 2-amino-5-bromopridine
- 2-amino-5-brompyridine
- 5-bromopyridine-2-amine
- A
- Maybridge1_001149
- F1995-0207
- FT-0611152
- PB30536
- Pyridine, 2-amino-5-bromo-
- Z57073814
- EINECS 214-019-9
- NSC-26282
- AC-907/34116004
- 1072-97-5
- UNII-D5QE8XW52U
- STR04388
- Q-101214
- CL0041
- Cambridge id 5121777
- Q27276127
- SCHEMBL22298049
- EN300-17910
- SB10592
- SCHEMBL105422
- AM20050651
- 5-bromo-2-amino-pyridine
- FT-0656478
- 6-amino-3-bromo-pyridine
- MFCD00006323
- 2-amino, 5-bromo-pyridine
- A2072
- DTXSID5022144
- CS-D1666
- 2-Amino-5-bromopyridine, 97%
- 2-amino-5 -bromopyridine
- FS-1054
- AC-031
- NS00023452
- BCP27587
- BB 0262959
- AKOS000112980
- HMS544M05
- 2-Amino-5-bromopyridin
- DB-027763
- STK024650
- 5-Bromopyridin-2-amine;5-Bromo-2-aminopyridine
- 5-bromopyridin-2-amine
- MDL： MFCD00006323
- Inchi： 1S/C5H5BrN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
- InChI Key： WGOLHUGPTDEKCF-UHFFFAOYSA-N
- SMILES： BrC1=CN=C(C=C1)N
- BRN： 108737

Computed Properties

Exact Mass: 171.96400
Monoisotopic Mass: 171.96361 g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 8
Rotatable Bond Count: 0
Complexity: 76.8
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Molecular Weight: 173.01
Surface Charge: 0
Tautomer Count: 2
XLogP3: 1.2
Topological Polar Surface Area: 38.9

Experimental Properties

Color/Form: White to Yellow Solid
Density: 1.6065 (rough estimate)
Melting Point: 136.0 to 141.0 deg-C
Boiling Point: 230.9±20.0 °C at 760 mmHg
Flash Point: 93.4±21.8 °C
Refractive Index: 1.5182 (estimate)
Water Partition Coefficient: Soluble in methanol, chloroform, ethyl acetate. Slightly soluble in water.
PSA: 38.91000
LogP: 2.00750
FEMA: 3202
Solubility: Not determined
Vapor Pressure: 0.1±0.5 mmHg at 25°C

5-bromopyridin-2-amine Security Information

Symbol:
Prompt：warning
Signal Word：Danger
Hazard Statement： H301,H315,H319,H335
Warning Statement： P261,P301+P310,P305+P351+P338
Hazardous Material transportation number：UN 2811 6.1/PG 3
WGK Germany：2
Hazard Category Code： 22-36/37/38
Safety Instruction： S26
FLUKA BRAND F CODES：10
Hazardous Material Identification：
Safety Term：S26
Risk Phrases：R22; R36/37/38
HazardClass：IRRITANT
Storage Condition：Keep in dark place,Inert atmosphere,Room temperature

5-bromopyridin-2-amine Customs Data

HS CODE：29333999
Customs Data：

China Customs Code:
2933399090

Overview:

2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-bromopyridin-2-amine Pricemore >>

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5-bromopyridin-2-amine Production Method

Production Method 1

13466-38-1

667-27-6

1072-97-5

832735-61-2

899452-26-7

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Acetonitrile ; rt → reflux; 1.5 h, reflux

Reference

Facile One-Pot Synthesis of N-Difluoromethyl-2-pyridone Derivatives

Ando, Makoto; et al, Organic Letters, 2006, 8(17), 3805-3808

5-bromopyridin-2-amine Raw materials

5-bromopyridin-2-amine Preparation Products

5-bromopyridin-2-amine Suppliers

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:1072-97-5)2-Amino-5-bromopyridine

Order Number:sfd16811;1690231

Stock Status:in Stock

Quantity:200kg/Company Customization

Purity:99.9%/98%

Pricing Information Last Updated:Friday, 19 July 2024 14:37

Price ($):discuss personally

Email:[email protected]

Product Official Link

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:1072-97-5)2-氨基-5-溴吡啶

Order Number:LE1690231;LE061

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:33

Price ($):discuss personally

Email:[email protected]

5-bromopyridin-2-amine Spectrogram

1H NMR

300 MHz

DMSO

13C NMR

5-bromopyridin-2-amine Related Literature

1. The acid-catalysed synthesis of 7-azaindoles from 3-alkynyl-2-aminopyridines and their antimicrobial activity

Tlabo C. Leboho,Sandy F. van Vuuren,Joseph P. Michael,Charles B. de Koning Org. Biomol. Chem. 2014 12 307
2. A cascade A3 coupling strategy towards the regioselective synthesis of β-carboline N-fused pyrrole derivatives with pyridine tethers

Vaishali,Chandi C. Malakar,Virender Singh New J. Chem. 2023 47 1186
3. The electric dipole moments of chloro-anilines and of some chloro-, bromo-, and nitro-substituted amino-pyridines in benzene and 1,4-dioxan solutions

C. W. N. Cumper,A. Singleton J. Chem. Soc. B 1968 645
4. Conversion of 2-deoxy-d-ribose into 2-amino-5-(2-deoxy-β-d-ribofuranosyl)pyridine, 2′-deoxypseudouridine, and other C-(2′-deoxyribonucleosides)

Colin B. Reese,Qinpei Wu Org. Biomol. Chem. 2003 1 3160
5. Halogen bonding directed supramolecular assembly in bromo-substituted trezimides and tennimides

Pavle Mocilac,John F. Gallagher CrystEngComm 2014 16 1893

Related Categories

Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Aminopyridines and derivatives

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