• 1. An assessment of strategies for the development of solid-state adsorbents for vehicular hydrogen storage
  Mark D. Allendorf,Alauddin Ahmed,Tom Autrey,Jeffrey Camp,Eun Seon Cho,Maciej Haranczyk,Abhi Karkamkar,Di-Jia Liu,Katie R. Meihaus,Iffat H. Nayyar,Roman Nazarov,Donald J. Siegel,Vitalie Stavila,Jeffrey J. Urban,Srimukh Prasad Veccham,Brandon C. Wood Energy Environ. Sci., 2018,11, 2784-2812
• 2. Acentric and chiral heterometallic inorganic–organic hybrid frameworks mediated by alkali or alkaline earth ions: synthesis and NLO properties
  Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
• 3. An investigation on the second-order nonlinear optical response of cationic bipyridine or phenanthroline iridium(iii) complexes bearing cyclometallated 2-phenylpyridines with a triphenylamine substituent?
  David B. Cordes,Alexandra M. Z. Slawin,Stefania Righetto,Denis Jacquemin,Eli Zysman-Colman,Véronique Guerchais Dalton Trans., 2018,47, 8292-8300
• 4. An intramolecular tryptophan-condensation approach for peptide stapling?
  Eunice Y.-L. Hui,Bhimsen Rout,Yaw Sing Tan,Kok-Ping Chan,Charles W. Johannes Org. Biomol. Chem., 2018,16, 389-392
• 5. An amorphous Cu–In–S nanoparticle-based precursor ink with improved atom economy for CuInSe2 solar cells with 10.85% efficiency?
  Green Chem., 2017,19, 1268-1277

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Glycosyl compounds

Comprehensive Overview of Adenosine 5’-Monophosphoramidate Sodium Salt (CAS No. 102029-68-5): Properties, Applications, and Research Insights

Adenosine 5’-Monophosphoramidate Sodium Salt (CAS No. 102029-68-5) is a specialized nucleotide derivative with significant relevance in biochemical and pharmaceutical research. This compound, often abbreviated as AMP-NH2·Na, features a unique phosphoramidate linkage, distinguishing it from conventional adenosine monophosphates. Its molecular structure combines adenosine, a ribonucleoside, with a monophosphoramidate group, making it a valuable tool for studying enzyme mechanisms, nucleic acid modifications, and signal transduction pathways.

In recent years, the demand for nucleotide analogs like Adenosine 5’-Monophosphoramidate Sodium Salt has surged due to their applications in drug discovery and biomedical research. Researchers frequently search for terms such as "AMP-NH2 sodium salt uses", "phosphoramidate nucleotide synthesis", and "CAS 102029-68-5 supplier", reflecting its growing importance. The compound’s stability and solubility in aqueous solutions, attributed to its sodium salt form, further enhance its utility in experimental settings.

One of the key hotspots in current research involves the role of modified nucleotides in mRNA vaccine technology and therapeutic oligonucleotides. While Adenosine 5’-Monophosphoramidate Sodium Salt is not directly used in vaccines, its structural analogs contribute to understanding nucleotide modifications that improve RNA stability and translational efficiency. This connection has spurred interest in related compounds, as evidenced by search trends like "nucleotide analogs for RNA therapeutics" and "phosphoramidate in drug delivery".

From a synthetic chemistry perspective, CAS No. 102029-68-5 serves as a building block for designing prodrugs and enzyme substrates. Its phosphoramidate moiety mimics natural phosphate groups, enabling studies on kinases and phosphatases—a topic frequently queried as "kinase assay substrates" or "phosphoramidate-based inhibitors". Additionally, the compound’s compatibility with HPLC and mass spectrometry makes it a preferred choice for analytical method development.

In the context of metabolic engineering, Adenosine 5’-Monophosphoramidate Sodium Salt is explored for its potential to modulate purine metabolism. Researchers investigating "ATP analogs" or "purine salvage pathways" often encounter this compound due to its structural similarity to AMP. Its applications extend to cell culture studies, where it aids in elucidating energy-dependent cellular processes.

Quality and sourcing are critical for researchers working with CAS 102029-68-5. Common search queries include "high-purity AMP-NH2 sodium salt" and "Adenosine 5’-Monophosphoramidate storage conditions". The compound typically requires storage at –20°C in a dry environment to maintain stability, a detail emphasized by suppliers and technical datasheets.

Looking ahead, the versatility of Adenosine 5’-Monophosphoramidate Sodium Salt positions it as a cornerstone in advancing precision medicine and biocatalysis. Its integration into high-throughput screening platforms and structural biology studies underscores its enduring value. As interest in personalized therapeutics grows, so does the demand for well-characterized nucleotide derivatives like this one.

For laboratories seeking reliable data, peer-reviewed studies on phosphoramidate chemistry and nucleotide analogs frequently cite CAS No. 102029-68-5. Its inclusion in databases such as PubChem and ChEBI ensures accessibility for global research communities, further solidifying its role in modern science.

• 61240-14-0(3'-Adenylic acid, monosodium salt (9CI))
• 4958-39-8(Adenosine-3'-monophosphate Sodium Salt)
• 133310-22-2(Adenosine, 5'-(hydrogentricyclo[3.3.1.13,7]dec-1-ylphosphoramidate), monosodium salt (9CI))
• 132-00-3(5'-Adenylic acid, monosodium salt)
• 6154-31-0(Adenosine, 5'-(hydrogenphosphoramidate) (8CI,9CI))
• 13474-03-8(Adenosine Phosphate Disodium)
• 4578-31-8(Adenosine 5’-Monophosphate Disodium Salt Hydrate)
• 149022-20-8(Adenosine 5'-Monophosphate (Sodium Salt Hydrate))
• 56351-06-5(Adenosine, 5'-[hydrogen (6-aminohexyl)phosphoramidate])
• 68694-63-3(Adenosine, 5'-(hydrogen phenylphosphoramidate) (9CI))