Cas no 1020252-99-6 (N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide)

N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide is a sulfonamide derivative featuring a bromo-substituted aromatic ring and a trifluoromethyl group, enhancing its reactivity and utility in organic synthesis. The presence of both electron-withdrawing groups (bromo and trifluoromethyl) makes it a valuable intermediate for nucleophilic substitution and cross-coupling reactions. Its ethyl sulfonamide moiety further contributes to its stability and solubility in organic solvents, facilitating its use in pharmaceutical and agrochemical applications. This compound is particularly suited for constructing complex molecules due to its selective reactivity and compatibility with diverse reaction conditions. Its well-defined structure ensures consistent performance in synthetic pathways.
N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide structure
1020252-99-6 structure
Product Name:N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide
CAS No:1020252-99-6
MF:C9H9BrF3NO2S
MW:332.137470960617
MDL:MFCD09972155
CID:857740
PubChem ID:46738702
Update Time:2025-05-20

N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide Chemical and Physical Properties

Names and Identifiers

    • 4-Bromo-N-ethyl-3-(trifluoromethyl)benzenesulfonamide
    • 4-Bromo-N-ethyl-3-(trifluoromethyl)-benzenesulfonamide
    • N-ETHYL 4-BROMO-3-TRIFLUOROMETHYLBENZENESULFONAMIDE
    • Benzenesulfonamide, 4-bromo-N-ethyl-3-(trifluoromethyl)-
    • MFCD09972155
    • 1020252-99-6
    • DB-371537
    • DTXSID70674358
    • AKOS015835259
    • CS-0211813
    • 4-Bromo-N-ethyl-3-(trifluoromethyl)benzene-1-sulfonamide
    • BS-19185
    • N-ethyl-4-bromo-3-trifluoromethylbenzenesulfonamide
    • N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide
    • MDL: MFCD09972155
    • Inchi: 1S/C9H9BrF3NO2S/c1-2-14-17(15,16)6-3-4-8(10)7(5-6)9(11,12)13/h3-5,14H,2H2,1H3
    • InChI Key: BTQIKMVDGYVIBP-UHFFFAOYSA-N
    • SMILES: C1(S(NCC)(=O)=O)=CC=C(Br)C(C(F)(F)F)=C1

Computed Properties

  • Exact Mass: 330.94900
  • Monoisotopic Mass: 330.94895g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 4
  • Complexity: 352
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.8
  • Topological Polar Surface Area: 54.6?2

Experimental Properties

  • Density: 1.610±0.06 g/cm3 (20 oC 760 Torr),
  • Solubility: Very slightly soluble (0.13 g/l) (25 o C),
  • PSA: 54.55000
  • LogP: 4.23780

N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide Customs Data

  • HS CODE:2935009090
  • Customs Data:

    China Customs Code:

    2935009090

    Overview:

    2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide Pricemore >>

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Additional information on N-Ethyl 4-bromo-3-trifluoromethylbenzenesulfonamide

N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide: A Comprehensive Overview

The compound N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide (CAS No. 1020252-99-6) is a highly specialized organic compound with significant applications in modern chemistry and materials science. This compound is characterized by its unique structure, which combines a sulfonamide group with a substituted aromatic ring containing bromine and trifluoromethyl substituents. The presence of these functional groups imparts distinctive chemical properties, making it a valuable component in various research and industrial settings.

Recent advancements in synthetic chemistry have enabled the precise synthesis of N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide through optimized reaction pathways. Researchers have explored the use of nucleophilic aromatic substitution and sulfonation techniques to achieve high yields and purity levels. The bromine atom at the para position of the aromatic ring plays a crucial role in directing the substitution reactions, while the trifluoromethyl group enhances the compound's stability and reactivity under specific conditions.

The sulfonamide group in N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide is known for its ability to form strong hydrogen bonds, making it an ideal candidate for applications in drug design. Recent studies have highlighted its potential as a lead compound in the development of novel pharmaceutical agents targeting specific biological pathways. Its ability to modulate enzyme activity and receptor binding has been extensively investigated, with promising results in preclinical models.

In addition to its pharmaceutical applications, N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide has found utility in advanced materials science. Its unique electronic properties make it a candidate for use in organic electronics, particularly in the development of semiconducting materials for flexible electronics and optoelectronic devices. Researchers have reported enhanced charge transport properties when this compound is incorporated into polymer blends, suggesting its potential for next-generation electronic applications.

The trifluoromethyl group in N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide contributes significantly to its chemical stability, particularly under harsh environmental conditions. This makes it an attractive option for use in industrial catalysts and corrosion-resistant coatings. Recent studies have demonstrated its ability to withstand extreme temperatures and chemical exposures, further expanding its potential applications across diverse industries.

From an environmental perspective, the synthesis and application of N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide have been carefully evaluated to ensure minimal ecological impact. Researchers have developed green chemistry approaches to minimize waste generation and energy consumption during its production process. These efforts align with global sustainability goals and underscore the importance of responsible chemical innovation.

In conclusion, N-Ethyl 4-Bromo-3-Trifluoromethylbenzenesulfonamide (CAS No. 1020252-99-6) stands as a testament to the ingenuity of modern chemical synthesis and its vast potential across multiple disciplines. Its unique structure, coupled with cutting-edge research findings, positions it as a key player in advancing both scientific discovery and industrial innovation.

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