Chemo-enzymatic three-step conversion of glucose to kojic acid?

Chemical Communications Pub Date: 2019-11-13 DOI: 10.1039/C9CC07405H

Abstract

Kojic acid is an important biomolecule, currently produced by fermentation and having a wide range of potential applications. A faster and more direct chemical route could open the door for its large-scale production and wider utilization in biorefineries. Here we describe an efficient method for the preparation of kojic acid from D-glucose via glucosone by a three-step chemo-enzymatic route.

Graphical abstract: Chemo-enzymatic three-step conversion of glucose to kojic acid
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