Chiral co-selector induced chirality switching in the enantioseparation of ofloxacin by forming a co-crystal?
New Journal of Chemistry Pub Date: 2019-08-28 DOI: 10.1039/C9NJ02921D
Abstract
A novel strategy for chirality switching in crystallization-based enantioseparation was developed through cocrystallization using chiral co-selectors. The reversal of chiral selectivity for separation of ofloxacin could be achieved by the combination of two specific tartaric acid derivatives, due to the spatial effects between the molecules.
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Journal Name：New Journal of Chemistry
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CAS no.: 89640-58-4
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