Cascade polycyclisations in natural product synthesis
Organic & Biomolecular Chemistry Pub Date: 2011-04-28 DOI: 10.1039/C1OB05212H
Abstract
The efficient, stereocontrolled construction of polycyclic ring systems has long presented a formidable challenge to synthetic chemists. Cascade reactions offer a ‘quick fix’—building multiple rings in a single step—and often dramatically shorten a synthetic route. In this Emerging Area article, a selection of the most recent and impressive examples of applications of this tactic to natural product synthesis are discussed, which demonstrate the ambition and achievements of the modern synthetic chemist.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4