Interactions of polysulfanes with components of red blood cells?

MedChemComm Pub Date: 2011-01-19 DOI: 10.1039/C0MD00203H

Abstract

Traditionally, the activity of most polysulfanes has been associated with the redox behaviour of the sulfur-sulfur bond. Here we show that polysulfanes, such as diallyltri- and tetrasulfide, also interact with cellular membranes and certain metalloproteins. Together, multiple interactions with various biological targets may explain best the biological activity of such compounds.

Graphical abstract: Interactions of polysulfanes with components of red blood cells
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