Activity-based probes as molecular tools for biomarker discovery
MedChemComm Pub Date: 2015-01-09 DOI: 10.1039/C4MD00417E
Abstract
Biomarker discovery and validation techniques have been extensively developed together with the “omics” era. Nevertheless, there is still a reduced number of biomarker candidates that surpass clinical trials every year. One of the drawbacks of biomarker discovery deals with the quantification of disease-related entities and its correlation with disease predisposition, disease stages or treatment response. Thus, activity-based profiling emerges as an exceptional tool for biomarker discovery and validation and this review highlights advances in this field.
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Journal Name：MedChemComm
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CAS no.: 89640-58-4
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