Design, synthesis and evaluation of novel 19F magnetic resonance sensitive protein tyrosine phosphatase inhibitors??
MedChemComm Pub Date: 2016-06-20 DOI: 10.1039/C6MD00277C
Abstract
Fluorine is a highly attractive element for both medicinal chemistry and imaging technologies. To facilitate protein tyrosine phosphatase (PTP)-targeted drug discovery and imaging-guided PTP research on fluorine, several highly potent and 19F MR sensitive PTP inhibitors were discovered through a structure-based focused library strategy.
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Journal Name：MedChemComm
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CAS no.: 89640-58-4
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