Synthesis of 2,3-Dihydro-6-methylthieno[2,3-c]furan (Kahweofuran), a Coffee Aroma Component, from an Acyclic Precursor
Journal of Chemical Research, Synopses Pub Date: DOI: 10.1039/A706334B
Abstract
Kahweofuran 1, one of the impact flavours of roasted coffee, was obtained from the acyclic unsaturated ester 8, produced in a Stobbe condensation of α-methylcinnamaldehyde with dimethyl succinate, through the key intermediate tetrahydrothiophene 14 and the C-7 derivatives 20 or 24, respectively.
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Journal Name：Journal of Chemical Research, Synopses
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CAS no.: 89640-58-4
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