Benzoyl methyl phosphate as an efficient reagent for the selective monobenzoylation of N-Bz-FTY720?
RSC Advances Pub Date: 2014-05-13 DOI: 10.1039/C4RA02401J
Abstract
A novel and efficient method for the selective monobenzoylation of N-Bz-FTY720 with benzoyl methyl phosphate (BMP) promoted by Zn(OAc)2 and Cs2CO3 was developed. Benzoyl methyl phosphate plays an important role as a biomimetic acylating agent for the monobenzoylation of 1,3-diols.
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Journal Name:RSC Advances
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CAS no.: 89640-58-4