Convergent micro-wave assisted synthesis of quinazolinone and its precursor using the bio-sourced solvent pinane?
RSC Advances Pub Date: 2023-07-10 DOI: 10.1039/D3RA03702A
Abstract
A general microwave synthesis of 4-oxo-3,4-dihydroquinazolin-2-yl propanoic acids and their diamide precursors from the corresponding substituted benzamide and succinic anhydride is described, using pinane as a sustainable solvent that favors the cyclization step. The conditions are some of the most simple and cost effective reported.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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