An unexpected copper(ii)-catalyzed three-component reaction of quinazoline 3-oxide, alkylidenecyclopropane, and water?
Chemical Communications Pub Date: 2014-06-27 DOI: 10.1039/C4CC04341C
Abstract
An unexpected copper(II)-catalyzed three-component reaction of quinazoline-3-oxide, alkylidenecyclopropane and water under mild conditions is reported. This transformation including [3+2] cycloaddition and intramolecular rearrangement leads to N-(2-(5-oxa-6-azaspiro[2.4]hept-6-en-7-yl)phenyl)formamides in good yields.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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