Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor?
Chemical Communications Pub Date: 2023-06-20 DOI: 10.1039/D3CC01946B
Abstract
Metal complexes introduced into protein scaffolds can generate versatile biomimetic catalysts endowed with a variety of catalytic properties. Here, we synthesized and covalently bound a bipyridinyl derivative to the active centre of an esterase to generate a biomimetic catalyst that shows catecholase activity and enantioselective catalytic oxidation of (+)-catechin.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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