Asymmetric PPCys: Strongly fluorescing NIR labels?

Chemical Communications Pub Date: 2010-06-11 DOI: 10.1039/C0CC00359J

Abstract

By a stepwise synthesis strategy biofunctionalized Pyrrolopyrrole Cyanines (PPCy) with an asymmetric substitution pattern were obtained. These exhibit extremely strong and narrowband NIR absorption and fluorescence. Internalization of a peptide bound PPCy is demonstrated using live cell microscopy.

Graphical abstract: Asymmetric PPCys: Strongly fluorescing NIR labels
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