Synthesis of trifluoromethyl N,N-aminals from nitrogen containing heterocycles by using a plasma flow microreactor?
Chemical Communications Pub Date: 2023-03-20 DOI: 10.1039/D3CC00942D
Abstract
Trifluoromethyl N,N-aminals are important precursors allowing access to fluorinated building blocks. In this work, the direct synthesis of trifluoromethyl N,N-aminals from nitrogen containing heterocycles is reported using argon plasma in a continuous flow microreactor without any additives or metal catalysts. Their transformation to N-trifluoroethyl amines is also reported.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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