An unusual silicon mediated transannular cyclopropanation?
Chemical Communications Pub Date: 2012-11-21 DOI: 10.1039/C2CC37739J
Abstract
A silicon mediated intramolecular 1,4-conjugate addition of a homoallylic carbon nucleophile leading to cyclopropanation is reported. Specifically, treatment of 6-trimethylsilyl-5,6-dihydroazocinones with fluoride gives 4-azabicyclo(5.1.0)octenones, presenting an unusual extension to the repertoire of silyl group reactivity.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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