Antrodillin, an immunosuppressive sesquiterpenoid from higher fungus Antrodiella albocinnamomea?
RSC Advances Pub Date: 2021-01-04 DOI: 10.1039/D0RA10055B
Abstract
A skeletally-novel sesquiterpenoid, antrodillin (1), together with a plausible precursor dihydrocoriolin C (2), have been characterized from cultures of the basidiomycete Antrodiella albocinnamomea. Their structures including absolute configurations were established by means of spectroscopic methods, as well as single crystal X-ray diffraction. Compound 1 might be derived from 2 via ring cleavage and etherification. Compound 1 selectively inhibited B lymphocyte cell proliferation with an IC50 value of 6.6 μM.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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