Total synthesis of Sparstolonin B, a potent anti-inflammatory agent?
RSC Advances Pub Date: 2015-01-15 DOI: 10.1039/C4RA15948A
Abstract
Two concise routes for the first total synthesis of Sparstolonin B (SsnB) have been described. The synthesis of SsnB could be accomplished in 5 and 6 steps with 40% and 38% overall yield, respectively. The rhodium-catalysed oxidative coupling of benzoic acid with internal alkyne was used in both strategies to construct the core structure of SsnB.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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