Synthesis of a novel crown ether derived from chiro-inositol and its catalytic activity on the asymmetric Michael addition

Chemical Communications Pub Date: 2003-06-16 DOI: 10.1039/B304649D

Abstract

A novel 18-membered chiral crown ether was prepared in four steps starting from L-quebrachitol, a chiro-inositol, and its catalytic activity in the Michael addition reaction of glycine imine with several Michael acceptors was studied.

Graphical abstract: Synthesis of a novel crown ether derived from chiro-inositol and its catalytic activity on the asymmetric Michael addition
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