An intracellular buildup reaction of active siRNA species from short RNA fragments?
Chemical Communications Pub Date: 2013-11-29 DOI: 10.1039/C3CC47529H
Abstract
Here we report a new strategy for the buildup reaction of active siRNA species from short RNA fragments in living cells using a chemical ligation reaction. This strategy could decrease undesired immune responses and provide more latitude for RNAi technology in the design and concentration of introduced RNA compared to traditional siRNA methods.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4