Positional assignment of differentially substituted bisaminoacylated pdCpAs?

Organic & Biomolecular Chemistry Pub Date: 2007-08-15 DOI: 10.1039/B708786A

Abstract

The synthesis and NMR analysis of a 2′-O-alanyl, 3′-O-[1-13C]valyl-pdCpA derivative has permitted the definitive assignment of the positions of acylation of tandemly activated pdCpAs, and the bisaminoacylated transfer RNAs derived therefrom.

Graphical abstract: Positional assignment of differentially substituted bisaminoacylated pdCpAs
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