O-Difluorodeuteromethylation of phenols using difluorocarbene precursors and deuterium oxide?
Organic & Biomolecular Chemistry Pub Date: 2018-02-08 DOI: 10.1039/C7OB03088F
Abstract
The first O-difluorodeuteromethylation of phenols using commercial diethyl bromodifluoromethylphosphonate and deuterium oxide to prepare various difluorodeuteromethyl aryl ethers is reported. This facile method affords a convenient way to introduce OCF2D groups into organic molecules.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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